Protein Info for DDA3937_RS15265 in Dickeya dadantii 3937

Annotation: MdtB/MuxB family multidrug efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1046 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 349 to 368 (20 residues), see Phobius details amino acids 374 to 396 (23 residues), see Phobius details amino acids 402 to 426 (25 residues), see Phobius details amino acids 446 to 466 (21 residues), see Phobius details amino acids 478 to 501 (24 residues), see Phobius details amino acids 542 to 563 (22 residues), see Phobius details amino acids 868 to 891 (24 residues), see Phobius details amino acids 909 to 937 (29 residues), see Phobius details amino acids 973 to 994 (22 residues), see Phobius details amino acids 1002 to 1028 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 19 to 1029 (1011 residues), 1169.9 bits, see alignment E=0

Best Hits

Swiss-Prot: 90% identical to MDTB_DICP7: Multidrug resistance protein MdtB (mdtB) from Dickeya paradisiaca (strain Ech703)

KEGG orthology group: K07788, RND superfamily, multidrug transport protein MdtB (inferred from 66% identity to azo:azo2334)

MetaCyc: 79% identical to multidrug efflux pump RND permease subunit MdtB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-352; TRANS-RXN-353; TRANS-RXN-92

Predicted SEED Role

"Multidrug transporter MdtB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SN34 at UniProt or InterPro

Protein Sequence (1046 amino acids)

>DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit (Dickeya dadantii 3937)
MQEPTPLQDATPLDGGGPSRLFILRPIATTLLMIAILLAGIVGYRALPVSALPEVDYPTI
QVVTLYPGASPDVMTSAVTAPLEHQFGSMSGLKQMSSQSSGGSSVITLQFQLTLPLDVAE
QDVQAAINAATNLLPGDLPFPPTYSKVNPADPPIMTLAVTSTALPLTQVQDMIETRIAQK
IAQVEGVGLVTLAGGQRPSVRVKLNPGALAAYGLSSETVRTAITAANVNTPKGSFDGPAR
AVTLSANDQMRSLDDYRQLIITWKNNAPVRLQDVATVEQAAENTYLAAWANQNQAIVLNI
QRQPGANVIATADHIRSLLPTLKASLPKSVDVALLTDRTTTIRASVDDVQFELILAIALV
VMVIYLFLRNAVATLIPSIAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIV
VIENIARYIEKGEKPLQAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIIGRLFREFAV
TLAVSILISAVVSLTLTPMMCARLLSHHSLSQQNRFTRASEKFFDWVIAWYGRGLTRVLS
HPWITLSVALSTLVLTILLYIVIPKGFFPIQDNGIIQGTVQASQTISFTGMVDKQQQVTS
LIMQDPAVESVSSFIGVDGTNPSLNSGRLQINLKPLDERSDRIQGVIERLQQRTSALPGV
QLYLQPVQDLTIDTQVSRTQYQFTLQTMSLAELSTWVPKLTAELQKLPQLQDVSSDWQDS
GAVAYLKVNRDSASRLGITMSQVDSALYNAFGQRLISTIYTQSNQYRVVLEQRHDSSNGL
AALDDIRLINSSGGVVPLSSIASVEERQGPLSINHIDQFPSTTISFNVAPGYALGDAVKA
IQETQQQMQLPSDIITRFQGSTLAFQSALTSTIWLVIAAVVAMYIVLGVLYESFIHPVTI
LSTLPTAGVGALLALMIAGSDLNIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMTPY
QAIYQACLLRFRPILMTTMAALLSAVPLMFSTGVGAELRRPLGICMVGGLVMSQVLTLFT
TPVIYLLFDRLALRLRRRQPQEGEAQ