Protein Info for DDA3937_RS15055 in Dickeya dadantii 3937

Annotation: formimidoylglutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02022: formiminoglutamate deiminase
  • amino acids 1 to 452 (452 residues), 651.9 bits, E=2.5e-200
• PF01979: Amidohydro_1
  • amino acids 47 to 427 (381 residues), 93.1 bits, E=1e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01673)

MetaCyc: 63% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

See E0SM98 at UniProt or InterPro

Protein Sequence (454 amino acids)

>DDA3937_RS15055 formimidoylglutamate deiminase (Dickeya dadantii 3937)
MSVYFATRALLPQGMARNVRLEVDELGYLQSVTPNAAPEGAQRLTGIVLPTVVNLHSHAF
QRAMAGLAEVAGHPQDSFWTWRDLMYRMVANLTPEQMGAIATRLYIDMLKGGYSQVAEFH
YLHHDPHGKPYRQHDMLRHVLAAAQRVGIGQTLLPVLYSYSGFGAQPPQPGQARFIQDVD
HYLRQQETLAALIQPYPLLNHGLCFHSLRAVSQNQMEDVLEATDSSLPVHIHIAEQQKEV
DDCLAWSGERPVQWLFNRFAVDARWCLVHATHLDEQELSRLAGSLAVAGLCPTTEANLGD
GIFPLDRYVAQGGRWGIGSDSHVSLNVVEELRWLEYGQRLRDRRRNRVATAQQPAVGSLL
YRQALQGGAQACRVPVGELSAGWRADWLVLREDALLSALPDDSLLNRWLFAGDRQQIRDV
WVAGKPVIEDGRHALDEEVDARFIEVMRTLQAVM