Protein Info for DDA3937_RS14970 in Dickeya dadantii 3937

Annotation: Zn-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF08240: ADH_N" amino acids 25 to 130 (106 residues), 122 bits, see alignment E=1e-39 PF00107: ADH_zinc_N" amino acids 171 to 297 (127 residues), 68.5 bits, see alignment E=5.8e-23

Best Hits

Swiss-Prot: 71% identical to RSPB_ECOLI: Starvation-sensing protein RspB (rspB) from Escherichia coli (strain K12)

KEGG orthology group: K08322, starvation sensing protein RspB [EC: 1.1.1.-] (inferred from 100% identity to ddd:Dda3937_01655)

Predicted SEED Role

"Starvation sensing protein RspB"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.-

Use Curated BLAST to search for 1.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SM79 at UniProt or InterPro

Protein Sequence (340 amino acids)

>DDA3937_RS14970 Zn-dependent oxidoreductase (Dickeya dadantii 3937)
MKSIVIEHPNALTIADRDLPQPAHGDVRVKVQLAGICGSDSHIYRGHNPFAKYPRVIGHE
FFGVIDAVGEGVDAARIGERVAVDPVVSCGHCYPCSVGRPNVCTALTVLGVHRDGGFSQY
AAVPARNAYRIPDSIPDEFAVMVEPFTIAANVAAQVRPTEQDTVLIYGAGPMGLTSMQVL
KGVYHVKDVIVVDRIPERLVMAQHCGADMVLDNREHPLAETLKQRGIQPTLIIDAACHPG
ILQEAISLASPAARIAIMGFSSEPSQITQQSITSKELSIFSSRLNAHKFPQVIEWLEQRL
IDPAKLITHRFHYADVVQAIDIFEKDQKRCCKVLLTFEEA