Protein Info for DDA3937_RS14105 in Dickeya dadantii 3937

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details PF10518: TAT_signal" amino acids 17 to 36 (20 residues), 23 bits, see alignment (E = 5.5e-09) TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 18 to 35 (18 residues), 18.3 bits, see alignment (E = 1.1e-07) PF13379: NMT1_2" amino acids 48 to 299 (252 residues), 338 bits, see alignment E=4.7e-105

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 100% identity to ddd:Dda3937_01845)

Predicted SEED Role

"Nitrate ABC transporter, nitrate-binding protein" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SKD2 at UniProt or InterPro

Protein Sequence (425 amino acids)

>DDA3937_RS14105 ABC transporter substrate-binding protein (Dickeya dadantii 3937)
MSDSTTDKKTDNQTNVFSRRQFLVGSAALGGAMLLPGIMNCAWAAGSDAPEKKEVRIGFI
PLTDCASVVMASVKGFDKKYGITIVPSKEASWAAVRDKLVSGELDAAHVLYGLLYGLQAG
AAGPQHNMAALMTLNNNGQAITLSNKLCEAGVTDGASLKRFIAASPAGTYTFAQTFPTGT
HAMWLYYWLGAAGINPFDDVRTVVVPPPQMVVNMKIGNMSGFCVGEPWNQRAITDGLGFT
AATSQDIWPDHPEKVLGTTAEWVNANPNTARALTAAVLDASRWIDSSDDNRRETARVIAG
RAYVNTQEETIAGRMLGQYDDGAGKRWQDAHAMRFYHDGEVNFPYLSDGMWFLTQHKRWG
LLAQEPDYQAVARQVNRIDIYKQAASAVGNVPLPSGEMRSSVLIDGKRWDGSDPAGYANS
FSVKK