Protein Info for DDA3937_RS13225 in Dickeya dadantii 3937

Annotation: PepSY domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 transmembrane" amino acids 45 to 69 (25 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 405 to 424 (20 residues), see Phobius details amino acids 456 to 482 (27 residues), see Phobius details PF03929: PepSY_TM" amino acids 44 to 429 (386 residues), 227.4 bits, see alignment E=1.8e-71

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_00028)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SHS3 at UniProt or InterPro

Protein Sequence (494 amino acids)

>DDA3937_RS13225 PepSY domain-containing protein (Dickeya dadantii 3937)
MSESKTETSFIQGGAVTNAPPAYDTYRNSRVRSQRVALQALLMRLHFYIGLFVGPFIFIA
ALTGTLYVLTPQIESKLYSHQLFTDTVGTPQLLSQQITAATHALGDKAQHARLIAVRPAP
EAGQTTRVMFSLPDLGPSESFAVFVDPVSLDIRGALTVYGTSGILPFRTSLDYLHRSLLL
GDIGRNYSELAASWLWIAALGGLYIWISTRKNHPRPRRRPAAERLSPVRQRQRLRGNHAA
TGLLLLVGLLFFSATGLTWSRWAGDNVAQLRAVMGWQTPSVNTRLDTASAPLPSAHAEHD
MMSMPMHPAAFQAAPQTFDSVLAAARAAGIDAGKIEIRPAARPERAWTVSEIDRAWPTQV
DAVAVDPMTFRVIDKVNFADYPLAAKLTRWGVDAHMGVLFGLPNQLLLSAFGIGLCSLIV
WGYRMWWTRRPTHASSHNPLQTLTTAFLQLNGRLRLLVLVIAGVLAVSLPVMGISLVMFL
LVDIWRWSRQRQTA