Protein Info for DDA3937_RS12865 in Dickeya dadantii 3937

Annotation: sulfonate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13379: NMT1_2" amino acids 27 to 242 (216 residues), 41.5 bits, see alignment E=4.5e-14 PF04069: OpuAC" amino acids 33 to 246 (214 residues), 28.8 bits, see alignment E=2.8e-10 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 33 to 315 (283 residues), 276.1 bits, see alignment E=1.5e-86 PF09084: NMT1" amino acids 72 to 242 (171 residues), 48.8 bits, see alignment E=2.5e-16 PF12974: Phosphonate-bd" amino acids 72 to 238 (167 residues), 39.2 bits, see alignment E=1.7e-13 PF16868: NMT1_3" amino acids 111 to 188 (78 residues), 27.1 bits, see alignment E=9.4e-10 PF00497: SBP_bac_3" amino acids 114 to 199 (86 residues), 32.6 bits, see alignment E=1.8e-11

Best Hits

Swiss-Prot: 74% identical to SSUA_ECOLI: Putative aliphatic sulfonates-binding protein (ssuA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 100% identity to ddd:Dda3937_03511)

MetaCyc: 74% identical to aliphatic sulfonate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-56-RXN [EC: 7.6.2.14]

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SGW0 at UniProt or InterPro

Protein Sequence (319 amino acids)

>DDA3937_RS12865 sulfonate ABC transporter substrate-binding protein (Dickeya dadantii 3937)
MLSRIKQAALTLLFSGALGVSALAHAASDPEQLRIGFQKGSVSLVLAKTHQLLEKQFPHT
KISWIEFPAGPQMLEALNIGSIDVGSTGDIPPLFAQAAGADLVYIGVEPPKPKAEVILVR
DDSPIKTVADLKGRKVAFQKGSSSHNLLLRNLQKAGLTFADIQPAYLTPADARAAFQQGN
VDAWAIWDPYYSAALLQGGVRVLADGTDLNLTGSFYLASRRYAEQHGVFLQQLLNTLTQA
DALTINQRSQSVTLLANAMGLPEAVISTYFDHRPLTVIKPVDERTLQAQQHTADLFYENR
LIPTRLDIASRIWRAPAAH