Protein Info for DDA3937_RS12830 in Dickeya dadantii 3937

Annotation: membrane integrity-associated transporter subunit PqiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 transmembrane" amino acids 53 to 77 (25 residues), see Phobius details amino acids 99 to 124 (26 residues), see Phobius details amino acids 145 to 163 (19 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 256 to 277 (22 residues), see Phobius details amino acids 304 to 330 (27 residues), see Phobius details amino acids 351 to 371 (21 residues), see Phobius details amino acids 378 to 401 (24 residues), see Phobius details TIGR00155: integral membrane protein, PqiA family" amino acids 4 to 409 (406 residues), 510.8 bits, see alignment E=1.5e-157 PF04403: PqiA" amino acids 52 to 201 (150 residues), 129.2 bits, see alignment E=6.2e-42 amino acids 254 to 409 (156 residues), 183.6 bits, see alignment E=1.2e-58

Best Hits

Swiss-Prot: 65% identical to PQIA_ECOLI: Intermembrane transport protein PqiA (pqiA) from Escherichia coli (strain K12)

KEGG orthology group: K03808, paraquat-inducible protein A (inferred from 100% identity to ddd:Dda3937_03519)

Predicted SEED Role

"Paraquat-inducible protein A" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SGV2 at UniProt or InterPro

Protein Sequence (422 amino acids)

>DDA3937_RS12830 membrane integrity-associated transporter subunit PqiA (Dickeya dadantii 3937)
MCVHHHHYDRHMLCPHCDLLVELPTLQDGQRAVCPRCKTALSSRRREPRWRPASFAFSAL
IMLLLSMLFPFVSMSVAGIRSEITLLEIPRVMVAENYASMATLFLLFSQLVPACSMAMIL
LLCLRAPLPDAVRRLFTRTLFQLKSWGMAEIFLAGVLVSFVKLMSYGDIGIGASFVPYIV
FCLLQLLAFQSLDRRWLWDDVAPPPPMPAGLETGRSGLDQGVRACTCCSAILPADELRCP
RCHTHGHARRRHSLQWTLALLLTSVLLYVPANVMPIMVTEALGHSITSTIMSGVILLWDS
GSWPVALVIFIASIMVPTLKMLAMGWLCWCAHGSRRYDTERLHLVYEVVEFVGRWSMIDV
FVIAVLSAMVRMGRLMSIYPAIGAVLFATVVILTMIAAMTFDPRLLWDRHHVQGEERSVD
EN