Protein Info for DDA3937_RS12825 in Dickeya dadantii 3937

Annotation: intermembrane transport protein PqiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details PF02470: MlaD" amino acids 43 to 134 (92 residues), 51.8 bits, see alignment E=4e-18 amino acids 158 to 234 (77 residues), 35.1 bits, see alignment E=6.6e-13 amino acids 287 to 389 (103 residues), 35.3 bits, see alignment E=5.6e-13

Best Hits

Swiss-Prot: 67% identical to PQIB_ECOLI: Intermembrane transport protein PqiB (pqiB) from Escherichia coli (strain K12)

KEGG orthology group: K06192, paraquat-inducible protein B (inferred from 100% identity to ddd:Dda3937_03520)

Predicted SEED Role

"Paraquat-inducible protein B" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SGV1 at UniProt or InterPro

Protein Sequence (548 amino acids)

>DDA3937_RS12825 intermembrane transport protein PqiB (Dickeya dadantii 3937)
MTKTNQGMAQIESIKRWSPVWIVPIVTVLIGAWILFYHVSHQGPEITLTTSNAEGIEAGK
TAIKSRSVNVGVVESVMLSEDLQQVEIKARLNDGMDKLLSKDSAFWVVKPQIGREGVSGL
GTLLSGSFIELQPGSNKEDSRAFKLLDSPPLASPDAKGIRIILNSEQSGQLTAGDPVLFR
GYRVGSVETSHFDPAARKMQYQLFVAAPYDQLVTANVRFWKDSGVALNLSAQGMRVEMGS
LSTLLSGGVSFDVPAGWEVGNPAHERDEFQLFDNQNSIQDSLYTEYKEYLLFFDESVRGL
QAGAPVEFRGIRLGTVAEVPFFPHNLPQSFDSDYRIPVLVRIEPGRLKQGLRDQINLEQE
LSKGAVSGMRASMKTANLLTGALYVDLDFYPQQKGRVTSLTSMDGYPVLPTVNGGLTQIQ
QKLMSVLDKINSLPLNPMVEQATKTLAESQSTLRELQKTLVSLNTLTNSEAMQQLPEDMQ
RTLRELNHSLQGVQPGSPAYNRMVGDMQRLDQTLRELQPLLRTLNDKSNALIFEAPGARD
PQPKKAKP