Protein Info for DDA3937_RS12795 in Dickeya dadantii 3937
Annotation: FAD-binding oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 80% identical to YDIJ_ECOLI: Uncharacterized protein YdiJ (ydiJ) from Escherichia coli (strain K12)
KEGG orthology group: K06911, (no description) (inferred from 65% identity to aha:AHA_2649)MetaCyc: 80% identical to D-2-hydroxyglutarate dehydrogenase (Escherichia coli K-12 substr. MG1655)
RXN-14932 [EC: 1.1.99.39]
Predicted SEED Role
"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)
MetaCyc Pathways
- superpathway of glycol metabolism and degradation (7/7 steps found)
- glycolate and glyoxylate degradation I (4/4 steps found)
- glycolate and glyoxylate degradation II (2/2 steps found)
- photorespiration II (7/10 steps found)
- photorespiration I (6/9 steps found)
- photorespiration III (6/9 steps found)
- glycolate and glyoxylate degradation III (1/3 steps found)
- L-lysine degradation V (3/9 steps found)
- superpathway of L-lysine degradation (12/43 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.1.99.14 or 1.1.99.39
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E0SGU5 at UniProt or InterPro
Protein Sequence (1019 amino acids)
>DDA3937_RS12795 FAD-binding oxidoreductase (Dickeya dadantii 3937) MIPQITQAPGIVQPVLSFLEALKQNGFTGDIATQYADRLTMATDNSIYQLLPDAVVFPRS TADVALLARLADEDRFRELVFTPRGGGTGTNGQALNHGIVVDMSRYMNRILEINPEQGWV RVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINTDASGQGSLVYGKTSDHVLGL RAVLPGGELLDTQAMPVALAEQLAQEDSPIGRIYHTVLHRCRERRELIVDKFPKLNRFLT GYDLRHVFSDDMQTFDLTRILTGAEGTLAFITEAKLDITPLPKVRRLVNVKYDSFDSALR SAPFMVEARALSVETVDSKVLNLAREDIVWHSVSELITDVPGEEMLGLNIVEFAGDDEPL IDGQVASLCERLDGLLAAREAGVIGYQVCRELAGIERIYGMRKKAVGLLGNSKGQAKPIP FAEDTCVPPQHLADYIVEFRALLDSHKLSYGMFGHVDAGVLHVRPALDMCDPQQEVLMKQ LSDQIVALTAKYGGLLWGEHGKGFRAEYSPAFFGPELYEELRRVKAAFDPDNRLNPGKIC APLGMDAPMMKVDAVKRGTYDRQIPLTVRTAYRGAMECNGNGLCFNFDTRSPMCPSMKIT GNRIHSPKGRATLVREWLRLLSEQGVDPLALENALPHQRVSFRGLIAKTRNTLAARQGVY DFSHEVKEAMSGCLACKACSTQCPIKIDVPGFRARFLQLYHTRYLRPARDYLVAGVESYA PLMAHSPKTFNFFLRQPWVNAVSRKFIGMVDLPLLSAPSLRRQFVGHRVMTTTLEQLEQM SPQARADHVLIVQDPFTSYYDAQVVADFVRLVEKLGLRPVLLPFSPNGKPQHIKGFLQRF AKTAGKTAEFLNRVARLGLPMVGVDPALVLCYRDEYREVLGDRRGDFQVQLVHEWLTALL TSRDDRAAALRDEPWYLFGHCTETTALPVSGQQWSAIFAHFGARLENVSVGCCGMAGTYG HETRNLAHSQGIYALSWQPSLQRLPQARCLTTGYSCRSQVKRMEGRGLKHPLQALLELV