Protein Info for DDA3937_RS12715 in Dickeya dadantii 3937

Annotation: glycoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02922: CBM_48
  • amino acids 48 to 107 (60 residues), 31.5 bits, E=1.8e-11
• PF00756: Esterase
  • amino acids 155 to 386 (232 residues), 73.1 bits, E=3.1e-24

Best Hits

Swiss-Prot: 70% identical to YIEL_ECOLI: Uncharacterized protein YieL (yieL) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_03836)

Predicted SEED Role

"Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Xylose utilization (EC 3.2.1.8)

MetaCyc Pathways

• (1,4)-β-D-xylan degradation (2/2 steps found)
• cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.8

Use Curated BLAST to search for 3.2.1.8

Sequence Analysis Tools

See E0SGS8 at UniProt or InterPro

Protein Sequence (394 amino acids)

>DDA3937_RS12715 glycoside hydrolase (Dickeya dadantii 3937)
MKTRKTCLCLLLSALSLSAPLAALAASGAIPALPRADVATRHYLSQVNADNSITFRLFAP
DAKAVSVVTGATPETWVAHPMMKNDLGVWSWRSEPQRPNLYEYFFNVDGFRSIDTGSALP
KPQRQVNTSMILVPGSVLDTRPVPHGELRTVTYHSASLKSERQVYVWTPPGYTGTGKPLP
VLYFYHGFGDAGDSAVAQGCIPQIMDNLLAEKKIAPMLVVIPDTETDAADAIAEDFAPKE
RRKTFYPRNAAAADRELIHDIIPLVNERFNVRRDADGRALAGLSQGGYQALVSGMSHLEH
FGWLATFSGVTTETVPNAQVTAQLSNAAGINQQLRNFTVAVGEKDTVTGKDIAGLKAQLE
QKGVKFDYRQYPGLGHEMDVWRPAYIEFVQKIFK