Protein Info for DDA3937_RS12550 in Dickeya dadantii 3937
Annotation: ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 53% identical to OPPA_SALTY: Periplasmic oligopeptide-binding protein (oppA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to ddd:Dda3937_04040)MetaCyc: 51% identical to oligopeptide ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]
Predicted SEED Role
"Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) or Sex pheromones in Enterococcus faecalis and other Firmicutes (TC 3.A.1.5.1)
Isozymes
No predicted isozymesUse Curated BLAST to search for 7.4.2.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E0SG16 at UniProt or InterPro
Protein Sequence (544 amino acids)
>DDA3937_RS12550 ABC transporter substrate-binding protein (Dickeya dadantii 3937) MTIDKGWIDKGWLASILGALSLTAVSVQAAEVPAGVQLADKQELVRANGSEPASLDPHKV ESDVEGNLIHDFFAKLVSVRDDGTVVPGLADRWENKDNQVWTFHLRPGLKWSDGSPITAD DVVFSWQRLVDPKTLSPYQTYVGSMHVLNAGDIIAGKKSPQELGIKALDKQTVQVTLEQP LSYFLPMVDHYVMVTVPKAAIEKFGDKWTQTANFVGSGPFIPTEWVVNERITAKRNANYW DNAHTVLNKVTYLAIVSNTAEVNRYKAGEVDATYTMPNQLFKSLKEELPNEVKVTPYLST YIYRFNTQKPPFNDPRVRRALDLALDKSVIAEKVLGQGQVPAYNYVPRGMAGYTSNQPEW AGWTQQQRNAEAKKLLKEAGYDQSHPLKFELLYNTSESHQKIAIAAASMWKQNLGAEATL LNQEWKTLLDTSRSGNFEVVRNSWGADYNEPSTYFDTLRANDSNNTGKFNDKAYDEVLDK AVKASSLDERSTLYHQAETILQQQMPLIPIYYYVRSQMVKPYVGGFKPDLKGDYYSKDIY IIKH