Protein Info for DDA3937_RS12220 in Dickeya dadantii 3937

Annotation: C4-dicarboxylic acid transporter DauA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 569 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details amino acids 324 to 343 (20 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 374 to 393 (20 residues), see Phobius details amino acids 411 to 442 (32 residues), see Phobius details TIGR00815: sulfate permease" amino acids 18 to 557 (540 residues), 427.2 bits, see alignment E=4.6e-132 PF00916: Sulfate_transp" amino acids 29 to 413 (385 residues), 272.6 bits, see alignment E=4.7e-85 PF01740: STAS" amino acids 463 to 558 (96 residues), 36.4 bits, see alignment E=3.8e-13

Best Hits

Swiss-Prot: 70% identical to DAUA_ECO57: C4-dicarboxylic acid transporter DauA (dauA) from Escherichia coli O157:H7

KEGG orthology group: K03321, sulfate permease, SulP family (inferred from 100% identity to ddd:Dda3937_00119)

MetaCyc: 70% identical to aerobic C4-dicarboxylate transporter DauA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-122A; TRANS-RXN0-553

Predicted SEED Role

"Putative sulfate permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SF61 at UniProt or InterPro

Protein Sequence (569 amino acids)

>DDA3937_RS12220 C4-dicarboxylic acid transporter DauA (Dickeya dadantii 3937)
MKSHRINGIRPFSALIEACWRETYTLSRFTHDVIAGITVGIIAIPLAMALAIASGVPPQY
GLYTSAIAGLVIALCGGSRYSVSGPTAAFVVILHPVSQQFGISGLLVATLLSGVFLLLMG
LCRLGRLIEYIPLPVTLGFTSGIAITIATMQVKDFFGLTMTTVPEHYAEKVAALVQALPT
LNIGDTLVGATTLLVLIVWPRLGIRLPGHLPALLAGTAVMGVLSLFQIDVATIGSRFSYL
LADGSHGQGIPAILPQFLLPWNIPTPDGHTMTLSWKSLSDLLPAAFSMAMLGAIESLLCA
VVLDGMTGRKHHPSSELIGQGIGNMVAPFFGGITATAAIARSAANVRAGATSPIAAVIHA
GLVLLSLLVLAPWLSYLPLSAMASLLLLVAWNMSEAHKVVYLLRRAPRDDILVLVLCMAL
TVLFDMVIAITVGIVLASLLFMGNVARMTRLSELPGTIAGQRLVLRINGPLFFAAAERLF
NELMERAQPYPTIILQWDAVSVLDAGGLNAFRHFVELLPPEKRLIITDIPFQPLKTLARA
NVTPIANRLVFYATLEQALAETTPHPDAV