Protein Info for DDA3937_RS11965 in Dickeya dadantii 3937

Annotation: carboxy terminal-processing peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF17804: TSP_NTD" amino acids 48 to 231 (184 residues), 200.9 bits, see alignment E=5.8e-63 TIGR00225: C-terminal processing peptidase" amino acids 193 to 550 (358 residues), 419.2 bits, see alignment E=5.6e-130 PF00595: PDZ" amino acids 240 to 319 (80 residues), 47 bits, see alignment E=7.1e-16 PF17820: PDZ_6" amino acids 259 to 318 (60 residues), 28 bits, see alignment 3.8e-10 PF03572: Peptidase_S41" amino acids 355 to 528 (174 residues), 167.7 bits, see alignment E=4.4e-53 PF11818: DUF3340" amino acids 536 to 666 (131 residues), 143.9 bits, see alignment E=1.1e-45

Best Hits

Swiss-Prot: 80% identical to PRC_ECOLI: Tail-specific protease (prc) from Escherichia coli (strain K12)

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to ddd:Dda3937_03783)

MetaCyc: 80% identical to tail-specific protease (Escherichia coli K-12 substr. MG1655)
C-terminal processing peptidase. [EC: 3.4.21.102]

Predicted SEED Role

"Tail-specific protease precursor (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SF06 at UniProt or InterPro

Protein Sequence (673 amino acids)

>DDA3937_RS11965 carboxy terminal-processing peptidase (Dickeya dadantii 3937)
MNKFVKAAALIWLLLSGCSFASENITRADQIPQLQPEAQHSTVSERVASRFLRSHYRQFM
LDAQFSGKIFDRYLNMLDYSHNVLLASDVAQFSGQKGELGDDLKSGKLSLPYAMYNLAQK
RRFERYQYALTLLEKPVNLNGNDVIDLDRAKAPWPQNVDELNALWDAKVKYDWLSLKLTG
KTDAEIKETLTKRYQFAIRRLVQTNSEDVFQLIMNAFAREIDPHTSYLSPRNTEQFNTEM
SLSLEGIGAVLQMDEDYTVINSMVPGGPAAKSKRISVGDRIVGVGQTGKPMVDVIGWRLD
DVVALIKGPKGSKVRLEVLPAGKGTKTQTITLTRERIRLEDRAVKMSIKDAGKDKVGVLD
IPGFYVGLTDDVKVQLQKLEKEHVSSIIIDLRGNGGGALTEAVSLSGLFIPTGPVVQVRD
NNGKVREDSDTDDTIYYKGPLVVLVDRFSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
QYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGNEMVDTGE
KFEDNALPWDSIKPASYTVMGDMKPLLPGLIDQHNARIARDPEFQYIQQDVARYQELKDK
RNHVSLNLVQRQKENNEDESTRLQRINDRLKRQGKPPLKSLDDLPKDYQDPDAYLNETVQ
IAEDLSKQEPKPQ