Protein Info for DDA3937_RS11525 in Dickeya dadantii 3937

Annotation: Fe(2+) transporter permease subunit FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 773 transmembrane" amino acids 286 to 311 (26 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 346 to 370 (25 residues), see Phobius details amino acids 393 to 414 (22 residues), see Phobius details amino acids 426 to 452 (27 residues), see Phobius details amino acids 458 to 477 (20 residues), see Phobius details amino acids 515 to 534 (20 residues), see Phobius details amino acids 679 to 700 (22 residues), see Phobius details amino acids 707 to 730 (24 residues), see Phobius details amino acids 736 to 757 (22 residues), see Phobius details PF09439: SRPRB" amino acids 3 to 129 (127 residues), 33.7 bits, see alignment E=7.4e-12 TIGR00231: small GTP-binding protein domain" amino acids 4 to 160 (157 residues), 54 bits, see alignment E=1.7e-18 PF01926: MMR_HSR1" amino acids 7 to 120 (114 residues), 76.3 bits, see alignment E=6.3e-25 PF02421: FeoB_N" amino acids 7 to 161 (155 residues), 219.4 bits, see alignment E=5.3e-69 TIGR00437: ferrous iron transport protein B" amino acids 11 to 702 (692 residues), 646.8 bits, see alignment E=3.8e-198 PF17910: FeoB_Cyto" amino acids 179 to 265 (87 residues), 57.2 bits, see alignment E=5.5e-19 PF07670: Gate" amino acids 355 to 448 (94 residues), 79 bits, see alignment E=1e-25 amino acids 516 to 705 (190 residues), 55.9 bits, see alignment E=1.6e-18 PF07664: FeoB_C" amino acids 459 to 511 (53 residues), 81.5 bits, see alignment 8.8e-27

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 100% identity to ddd:Dda3937_02094)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SDG4 at UniProt or InterPro

Protein Sequence (773 amino acids)

>DDA3937_RS11525 Fe(2+) transporter permease subunit FeoB (Dickeya dadantii 3937)
MSTQPVICVVGNPNCGKTTLFNVLTGGKQTVGNWPGVTVEKKVGSYRYQQQQVTLVDLPG
VYSLNPSSESSEDERVARDYILSGEANLVLNIVDASNLERNLYLTAQLLDMQVPMVVAVN
MMDIATARKLDIDIAGLQQRLGCPVIPITASQKKGIEMLHEVCQAALAQPVIPPVSIPYD
APLSRAAQAIAERLQGQPAIRNPHWLAIQLLEGDVTVRNRVTADALAFADAQVTRLVAEY
EDELDIFLADARYQFVGTVAREVITRRGEVSATLTDKIDRVVLHRFFGIPIFLLVMYLMF
VFTINVGSAFIDFFDKLFGALLVEGFGELLLAMHTPEWLKTLLADGVGGGIQTVSTFIPV
IGCLYLFLSWLEDSGYMARAAFVMDRFMRSIGLPGKAFVPLIVGFGCNVPAVMATRTMER
HSDRVVTVMMAPFMSCGARLPVYVLFASALFVEGGQNMVFGLYLVGIAAAIATGFLLKNT
ALKGDASAFVMEIPPYHLPSLRSVLIRTWERLKGFLLRAGRLIVVVVTVLGFLNSMGTDG
SFGNQNTQKSVLSAVGQAIVPVFKPMGIREENWPAAVGVFTGIFAKEAVVGTLDSLYGAM
AASQSGGAKEEKTFSLTGGIHDALATIPENLGKLGDALLNPMGINVGDLTDTDTIAKDNK
FSVTSLTVISQMFDGRLGAFSYLLMVLLYIPCVAAVSAIWREVGTAWTLFCAGWTIQVGY
STAVVVYQIGRFAQHPLYSLCALLGVAAMLCVTVMLLRRNGLQRQRMAVGEAK