Protein Info for DDA3937_RS10150 in Dickeya dadantii 3937

Annotation: prolyl oligopeptidase family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 PF02897: Peptidase_S9_N" amino acids 4 to 404 (401 residues), 356 bits, see alignment E=2.6e-110 PF00326: Peptidase_S9" amino acids 462 to 678 (217 residues), 232 bits, see alignment E=5.8e-73

Best Hits

Swiss-Prot: 62% identical to PTRB_ECOLI: Protease 2 (ptrB) from Escherichia coli (strain K12)

KEGG orthology group: K01354, oligopeptidase B [EC: 3.4.21.83] (inferred from 100% identity to ddd:Dda3937_03570)

MetaCyc: 62% identical to oligopeptidase B (Escherichia coli K-12 substr. MG1655)
Oligopeptidase B. [EC: 3.4.21.83]

Predicted SEED Role

"Protease II (EC 3.4.21.83)" (EC 3.4.21.83)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SB93 at UniProt or InterPro

Protein Sequence (683 amino acids)

>DDA3937_RS10150 prolyl oligopeptidase family serine peptidase (Dickeya dadantii 3937)
MKAPQAEKRPHAITMHGDTRIDNYYWLRDDERNNPDVLAWLQEENRYCDRVMAPHAALRQ
SLYEEMVARIPGEDVSVPYVKRGYRYQSRYEPGKDYAIYQRQPEQETGSDAWQVLLDGNQ
RADGSEFYSLGALGVSPDNRLMSVAEDLLSRRQYVVTFRDLDTGEWLADRLENVSAGSEW
AADSRTLYYVRKNPQTLLPYQVYRHRLGEDPQQDELVYEETDDAFYLSLDKTTSERYILI
YLDSTTSTEILLLDAADPQAKPQLFVPRRPDHEYVVDHFRDAFYVRSNKDGKTFGFYRAH
DASESTWDALIAPRQERVLEGFSLFDDWYVVEERERGLTHIRYIHWQTEESRQIAFSDPA
YVTWLSYNPTPESTQLRYGYSSMTTPMTIYELDMATGVQVALKQSEVKNFDAGNYRSERL
WVTARDGESVPVSLVYHKDCELAQSPLLVYGYGAYGSSMDPEFSSSRLSLLDRGFVYALA
HIRGGGELGQQWHDQGRLSNKMNTFTDFIDVTQALLARGYGDSTKTFAMGGSAGGLLMGA
VINMAPSLFSGVVAQVPFVDVLTTMLDESIPLTTGEYDEWGNPNHERDYQYIKQYSPYDS
VSAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLHTDMGSGHGGKSGRLA
QFEDIAQEFTFLLMVLNHQPVLK