Protein Info for DDA3937_RS10095 in Dickeya dadantii 3937
Annotation: zinc ABC transporter ATP-binding protein ZnuC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 86% identical to ZNUC_PECAS: Zinc import ATP-binding protein ZnuC (znuC) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
KEGG orthology group: K09817, zinc transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to ddd:Dda3937_01624)MetaCyc: 78% identical to Zn2+ ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]
Predicted SEED Role
"Zinc ABC transporter, ATP-binding protein ZnuC" in subsystem Transport of Zinc
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.-
Use Curated BLAST to search for 3.6.3.- or 7.2.2.20
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E0SAW9 at UniProt or InterPro
Protein Sequence (252 amino acids)
>DDA3937_RS10095 zinc ABC transporter ATP-binding protein ZnuC (Dickeya dadantii 3937) MSTLVSLENIGVQFGNKPVLNDISLTLQAGRILTLLGPNGAGKSTLVRVVLGLQTPTRGT LTRAANLRIGYVPQKLHLDPTLPLTVKRFMQLRPGVNKQDIMPVLKRVQAGHLLEQPMQK LSGGETQRVLLARAILARPQLLVLDEPTQGVDVNGQLALYELINQLRQEYQCGVLMVSHD LHLVMAKTDEVLCLNQHICCSGTPEVVSLHPEFLAMFGHRGAGQLAIYRHHHNHRHDLNG KIILKRQDGNHA