Protein Info for DDA3937_RS09750 in Dickeya dadantii 3937

Annotation: HAMP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 654 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 281 to 305 (25 residues), see Phobius details PF00672: HAMP" amino acids 318 to 355 (38 residues), 30.4 bits, see alignment 3.9e-11 PF00015: MCPsignal" amino acids 418 to 573 (156 residues), 183.3 bits, see alignment E=3.8e-58

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to ddd:Dda3937_02970)

Predicted SEED Role

"Methyl-accepting chemotaxis protein IV (dipeptide chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SAP6 at UniProt or InterPro

Protein Sequence (654 amino acids)

>DDA3937_RS09750 HAMP domain-containing protein (Dickeya dadantii 3937)
MGFSSTIKNTKISHKLYLGFGVVLLLVVMASSLSAIRFRDIRDIYDKTNLIYNINIEVFQ
AKINRLKYFYTPDDSTQAVLTGFVKHAAELTQSAHTLSWHSDELGYINDLDKVMVDFQKS
VADMSTATQQVVALRKQIATLNAQDAVKSFRDGLQNQQLDSALYQRVDELAYATASLKNL
SYELQLTGTDDAAKAFNSRYAEVQKAYQALLPTLSGDTQKLAEALWKYTAQYASQNQDYS
RAWSDLKKAENAVKIGGDKSSAVIKSLITTVKNQNDALAYGSANITLLIGLIAVVIGILI
AVYIIRQITRPVMHNLMLAERIASGDLTATIEVDRHDELGKLTAAMAAMNDRLRQMISDV
RDSVGHVTHSAADIAAGNSDLASRTEQQSAAVVQTAASMEELTSTVKNNTENARHASQIA
SDASQNAHKGGEVVQNVVKTMDDIAASSRKIADITAVINSIAFQTNILALNAAVEAARAG
EQGRGFAVVAGEVRNLSQRSSQAAKDIAALIAESVERTNAGSTLVAEAGQTMESIVNSVS
RVNDIMGEISSASEEQSRGIEQISRAITELDSTTQQNAALVSQSSSAANTLEEQAMLLEK
LVATFRLSESSAPSARPAPLNNPRRPLQALPAAGKSKALAKPAAKGQQDDWASF