Protein Info for DDA3937_RS09595 in Dickeya dadantii 3937

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1176 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 191 (172 residues), 155.3 bits, see alignment E=2.6e-49 PF17854: FtsK_alpha" amino acids 686 to 786 (101 residues), 103 bits, see alignment E=1.8e-33 PF01580: FtsK_SpoIIIE" amino acids 794 to 1007 (214 residues), 281.6 bits, see alignment E=8.4e-88 PF09397: FtsK_gamma" amino acids 1111 to 1171 (61 residues), 93.3 bits, see alignment 1.2e-30

Best Hits

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 100% identity to ddd:Dda3937_00129)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SMX6 at UniProt or InterPro

Protein Sequence (1176 amino acids)

>DDA3937_RS09595 DNA translocase FtsK (Dickeya dadantii 3937)
MSQEYTEDKDVTLKKLSAGRRLLEAMLIVVVLFAIYLAVALLSFSPSDPSWSQTAWHEPI
HNLGGGVGAWLADTLFFIFGVLAYAIPVVMVSLCWVIHRQRGQRATLDYFTLSLRLIGTL
ALILTSCGLAALNVDDIYYFASGGVLGSLLSSSMIPRFNNIGGTMILLCVWAAGLTLFTG
WSWLTIAEKLGAGVMGCLTLFSGRRREDDYLYDDDDEDIDESPAEARKDAHRTAAPHETE
PAAISSSSAEEDDDDVLFSAPGVTATSGAVAAASVAAEMPAADEASGRAFATAAAPDAEP
VLKPHPEPIAVTPFAEPESYVPPVATPAPEFRPGVDISAVSPLTPASAGVMPAPVNLASS
LSEPLPDWQPLTVQADDRIARTAAAAVTAATIVSGSAEAAPAPKSESQNATLFMPAFTTD
EDNNPQVKRGMGPELPRPNPVRIPTRRELASYGIKLPSQRLAEQQAREAEQQAQTTHVEQ
TGALTPFAAHVPLPDDVTAQTALPEDEQDALIQDAALRQAFADQQRERYGESYPDHEEDE
ETLLQAQLARDFADMQRSRYAEERELDTKQDEPAIFAAEPPAVTPAAAETRQPDLKPKTE
PPLDSAFAISPFADLVDDGPVEPLFTLPPQESFPGEPRYVQSPALQTVAPIESEAEAESP
SSIMDSLIHPFLMRNDQPLHKPTTPLPSLDLLTPPSMNDAPVDRDALDDMARLIETRLAD
YRVKATVVDYHPGPVITRFELDLAPGVKAARISNLARDLARSLSVVAVRIVEVIPGKPYV
GLELPNRYRQTVFLREVLDCDRFRDNASPLAIVLGKDISGQPVVADLAKMPHLLVAGTTG
SGKSVGVNAMIISMLYKATPADVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALR
WCVGEMERRYKLMSALGVRNLSGYNERVMQAEAMGRPVPDPFWKPGDSMDTQPPVLEKLP
YIVVMVDEFADLMMAVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPT
RIAFTVSSKIDSRTILDQGGAESLLGMGDMLYMAPNSSIPIRVHGAFVRDQEVHAVVQDW
KARGRPEYIDNIISGDDDGEGGSLGFDGDEDLDPLFDQAVAFVVEKRRASISGVQRQFRI
GYNRAARIVEQMEMQGIVSAPGHNGNREVLAPPPME