Protein Info for DDA3937_RS09545 in Dickeya dadantii 3937

Annotation: ATP-dependent endonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 PF11398: DUF2813" amino acids 1 to 376 (376 residues), 516.1 bits, see alignment E=1.8e-158 PF13175: AAA_15" amino acids 1 to 52 (52 residues), 41 bits, see alignment 4.8e-14 PF13555: AAA_29" amino acids 11 to 50 (40 residues), 30.6 bits, see alignment 5.8e-11 PF20469: OLD-like_TOPRIM" amino acids 377 to 441 (65 residues), 53.2 bits, see alignment E=8.9e-18

Best Hits

Swiss-Prot: 66% identical to YBJD_ECOLI: Uncharacterized protein YbjD (ybjD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_02366)

Predicted SEED Role

"Predicted ATP-dependent endonuclease of the OLD family, YbjD subgroup"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SMW6 at UniProt or InterPro

Protein Sequence (553 amino acids)

>DDA3937_RS09545 ATP-dependent endonuclease (Dickeya dadantii 3937)
MYLERVEILGFRGINRLSLTLDDNTVLIGENAWGKSSLLDALSLLLTPSPPLYHFDLQDF
HFTPGDETSRERHLQVIFTFCESAPGHHLAPRYRSLSPVWIKGEGRLHRIFYRLEGEMDE
SQAIFTWRSFLDANGQALPLDNIDWLAGEVIRLHPVLRLRDARFIRRFRTGTLMPQIDDN
DRLSRQFETLVRELAQNPNRLTNQELRQGLVAMRQLVEHYFSEQGADPNDRRHHRHARAG
NGRAWRSLDNINRMISGPNSRSRRIILLELFSTLLQAKGSAALDPHARPLLLIEDPETRL
HPIMLSVAWGLLTQLPLQKITTTNSGELLSLVPVEQVCRLVRESAKVATYRIGRQGMTQE
DSRRITFHIRFNRPASLFARCWLLVEGETEVWMLNELARQCGHHFEAEGVRVIEFAQVGL
KPLLKFAYRMGIEWHVLVDGDDAGKKYAATARSLLQAQNESERDHLTVLPALDMEHFMYR
NGFSQVYHRVAQLPEPVPLSAAKVITKAIHRTSKPDLAIEVALEAASLGESAIPPLIRGM
FSRVLWLARGRAD