Protein Info for DDA3937_RS09225 in Dickeya dadantii 3937

Annotation: sugar efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 51 to 72 (22 residues), see Phobius details amino acids 84 to 101 (18 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 219 to 240 (22 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 283 to 302 (20 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 369 to 390 (22 residues), see Phobius details TIGR00899: sugar efflux transporter" amino acids 19 to 392 (374 residues), 627.4 bits, see alignment E=4.4e-193 PF07690: MFS_1" amino acids 21 to 345 (325 residues), 129 bits, see alignment E=2.1e-41 amino acids 270 to 390 (121 residues), 40.2 bits, see alignment E=2e-14 PF12832: MFS_1_like" amino acids 28 to 343 (316 residues), 55.8 bits, see alignment E=4.4e-19

Best Hits

Swiss-Prot: 100% identical to SOTA_DICCH: Sugar efflux transporter A (sotA) from Dickeya chrysanthemi

KEGG orthology group: K03291, MFS transporter, SET family, sugar efflux transporter (inferred from 100% identity to ddd:Dda3937_03626)

MetaCyc: 68% identical to sugar exporter SetB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-82

Predicted SEED Role

"Sugar efflux transporter B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SM04 at UniProt or InterPro

Protein Sequence (393 amino acids)

>DDA3937_RS09225 sugar efflux transporter (Dickeya dadantii 3937)
MTISSARTARRLPDLTSSAFLVIAFLTGIAGALQLPTLSLFLSTEVQVRPFMVGLFYTGS
AVIGIVVSQILATYSDRQGDRKTLILQCCLLGALACLLYAWNRNYFVLLFIGVLLSSFGS
TANPQLFALAREHADRTGRGAAMFSSVMRAQISLSWVIGPPVAFALALGFGFPAMYLTAA
VVFVLCGLLVWLLLPSMPKTRVKSAATLESPRQNRRDTLLLFTACTLMWTCNGIYLINMP
LYLVNELRLPEKLAGVMMGTAAGLEIPVMLLAGYLTSRLGKRLLMRLAVIAGLIFYTGLT
LLNGSWALLALQLLNAIFIGILAGMGMLYFQDLMPGQAGAATTLFTNTTRVGWIISGSLA
GIVAEVWSYHAGFVIAIAMLAGAAVCMWRIRDV