Protein Info for DDA3937_RS09200 in Dickeya dadantii 3937

Annotation: phosphatase PAP2 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 63 to 81 (19 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 153 to 180 (28 residues), see Phobius details amino acids 191 to 212 (22 residues), see Phobius details PF01569: PAP2" amino acids 139 to 211 (73 residues), 37 bits, see alignment E=1.3e-13

Best Hits

Swiss-Prot: 61% identical to LPXT_ECOLI: Lipid A 1-diphosphate synthase (lpxT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_03831)

MetaCyc: 61% identical to lipid A-core phosphotransferase (Escherichia coli K-12 substr. MG1655)
Undecaprenyl-diphosphatase. [EC: 3.6.1.27]; RXN-16281 [EC: 3.6.1.27, 2.7.4.29]; 2.7.4.29 [EC: 3.6.1.27, 2.7.4.29]

Predicted SEED Role

"Putative membrane protein"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.27

Use Curated BLAST to search for 2.7.4.29 or 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SLZ8 at UniProt or InterPro

Protein Sequence (237 amino acids)

>DDA3937_RS09200 phosphatase PAP2 family protein (Dickeya dadantii 3937)
MSKRSKLLILLFNLLGFSLFFSWYLPAQHGFWFDIDTSLFFYFNQRLATSSAFLHLVAIT
NNRAFDACALLAMGLLYLCYYLRRSHDARRQMLFIGLVMLMTAVVLNQLGHLIPIQHSSP
TLFFSDINRVGDLTGIPTKDASSDSFPGDHGMMLMIFAAFMLRYFGRLAFAVSLLIVLVF
ATPRIMIGAHWFTDVAVGSLSIVLVGLSWWLLTPACDALIRWLDHLLPGKKSLSQQA