Protein Info for DDA3937_RS09060 in Dickeya dadantii 3937

Annotation: DUF927 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 898 transmembrane" amino acids 513 to 530 (18 residues), see Phobius details PF08273: Prim_Zn_Ribbon" amino acids 36 to 72 (37 residues), 46.6 bits, see alignment (E = 5.2e-16) PF13362: Toprim_3" amino acids 212 to 308 (97 residues), 49.2 bits, see alignment E=9e-17 PF06048: DUF927" amino acids 349 to 626 (278 residues), 167.3 bits, see alignment E=9.1e-53

Best Hits

KEGG orthology group: K06919, putative DNA primase/helicase (inferred from 100% identity to ddd:Dda3937_02198)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SLW9 at UniProt or InterPro

Protein Sequence (898 amino acids)

>DDA3937_RS09060 DUF927 domain-containing protein (Dickeya dadantii 3937)
MRNIDFIREVTRSAVGRWPDVLALLGIEVPRHPTTHTPCPACGGTDRFQFDNLDGRGTWH
CRHCDPEAGDGLALVMNVRQCNAADAARLVADVLGMPAGAPAPDTHDTRQSPSADEQTRT
AEKARRFAARLKKLTAQAQPGESAYLAGKGLTGFSYPLLPDGTLLLTLQDASGTTTAAAQ
TISPDGRKRQVADSAKRGAYHAVNSPAQPDTVIIAEGLATALSVHQMCPEALTLAAIDAG
NMVPVAKAMRTRYARAHIILAADNDIKPDTPNAGKDWAEKAARAVNGQVALPPTDTKADW
DDYRQQYGLMAATQAFAASLYSPPADEPDDNKLAPSDPLKPHVQSRRDGVFWVTPKVDKD
SGEIINNESWLCSPLAVVGIGRDDKDQYLIMRWRPFGAKADTTQAIPLADIGEREGWRTL
KNGGVNVTTKNSLRAILADWLQRSAARDIWHIAHATGWQCGAYLMPDGEIIGTPDRPVLF
SGRSAAAAGYTVSGTAEGWRDTVARLAGGNYAMMTGIAAALAAPLIGLVGADGFGIHFYE
QSSAGKTTAASVATSLYGNPELLRLTWYGTALGLANEAAAHNDALMPLDEVGQGADPVSV
AQAAYALFNGVGKLQGAKEGGNRELKRWRTVAISTGEMDLETFIASVGRKTKAGQLVRLL
NIPLSKTARFHEHANGKQHADALKDACQQYHGAAGRAWIKHLADHPQQAIEAVRAAETRW
RSLIPADYGEQVHRVAARFAVMEAALSLGRVITGWDEQTGRDAIQHSFNAWVREFGTGNK
EHQQIIEQCEAFLNAHGLSRFAPLPYNPHDLPIRDLAGYRDRGKHDAAPMVFYTFPATFE
GEIARGFNVRQFAEILRGAGMLTPPTSGRGYQRKSPRIDGRQINVYVLQYRPEDDSPE