Protein Info for DDA3937_RS08020 in Dickeya dadantii 3937

Annotation: CDP-diacylglycerol diphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details PF02611: CDH" amino acids 34 to 252 (219 residues), 275.2 bits, see alignment E=2.2e-86

Best Hits

Swiss-Prot: 45% identical to CDH_YERPE: CDP-diacylglycerol pyrophosphatase (cdh) from Yersinia pestis

KEGG orthology group: K01521, CDP-diacylglycerol pyrophosphatase [EC: 3.6.1.26] (inferred from 100% identity to ddd:Dda3937_03000)

MetaCyc: 41% identical to CDP-diacylglycerol diphosphatase (Escherichia coli K-12 substr. MG1655)
CDP-diacylglycerol diphosphatase. [EC: 3.6.1.26]

Predicted SEED Role

"CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 3.6.1.26)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SJ94 at UniProt or InterPro

Protein Sequence (255 amino acids)

>DDA3937_RS08020 CDP-diacylglycerol diphosphatase (Dickeya dadantii 3937)
MIRKKYLIGLIVTLLLVALLLYFWQPFARRGNGNALWEFVGQQCVPNQQKNNSPAPCLEV
NLQGHYALFKDRRGPYHDLLIPTDRISGIESPLLLQAGTPAYFAAAWSYRDRLSRQMGKP
IGDDKLGLAINSLYGRTQGQLHIHISCLKPEVYQTLRARNANIGYDWVSLGQPLLGHDYL
AIKLNGSDLTRTDPFKLLNQYVQTREDRMENYGLALTANTQGELILLAVRRDFIGLFNRG
SAEEILDVNCALAQP