Protein Info for DDA3937_RS07675 in Dickeya dadantii 3937

Annotation: CRISPR-associated endonuclease Cas2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 97 TIGR01573: CRISPR-associated endonuclease Cas2" amino acids 1 to 87 (87 residues), 51.2 bits, see alignment E=5.9e-18 PF09827: CRISPR_Cas2" amino acids 1 to 78 (78 residues), 83.2 bits, see alignment E=5.9e-28

Best Hits

Swiss-Prot: 62% identical to CAS2_DESVH: CRISPR-associated endoribonuclease Cas2 (cas2) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_02863)

Predicted SEED Role

"CRISPR-associated protein Cas2" in subsystem CRISPRs

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SIE1 at UniProt or InterPro

Protein Sequence (97 amino acids)

>DDA3937_RS07675 CRISPR-associated endonuclease Cas2 (Dickeya dadantii 3937)
MMVLITYDVSLEDANGPRRLRQLAKICLDYGVRVQYSVFECDVDAAQWVVLRQKLLTTYD
ERVDSLRFYRLGKGWRDKVEHHGAKPALDIFGDTLIV