Protein Info for DDA3937_RS06695 in Dickeya dadantii 3937

Annotation: dCTP deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02274: deoxycytidine triphosphate deaminase
  • amino acids 2 to 190 (189 residues), 224 bits, E=5.8e-71
• PF06559: DCD
  • amino acids 3 to 125 (123 residues), 30.4 bits, E=1.8e-11
• PF00692: dUTPase
  • amino acids 77 to 184 (108 residues), 34.7 bits, E=1.4e-12

Best Hits

Swiss-Prot: 94% identical to DCD_PECCP: dCTP deaminase (dcd) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 100% identity to ddd:Dda3937_03932)

MetaCyc: 90% identical to dCTP deaminase (Escherichia coli K-12 substr. MG1655)
dCTP deaminase. [EC: 3.5.4.13]

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (14/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (7/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Sequence Analysis Tools

See E0SFS9 at UniProt or InterPro

Protein Sequence (193 amino acids)

>DDA3937_RS06695 dCTP deaminase (Dickeya dadantii 3937)
MRLCDRDIETWLDDGRLSITPRPPIERINGATVDVRLGNQFRVFSGHTAPFIDLSGPKDE
VSAALDRVMSDEINLVEGDAFFLHPGELALAVTLESVTLPDNLVGWLDGRSSLARLGLMV
HVTAHRIDPGWQGCIVLEFYNSGKLPLALRPGMIIGALSFEPLSGPAARPYNRREDAKYK
DQQGAVASRIDKD