Protein Info for DDA3937_RS06555 in Dickeya dadantii 3937

Annotation: CDF family zinc transporter ZitB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 80 to 104 (25 residues), see Phobius details amino acids 116 to 139 (24 residues), see Phobius details amino acids 152 to 177 (26 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details TIGR01297: cation diffusion facilitator family transporter" amino acids 16 to 290 (275 residues), 316.4 bits, see alignment E=8.3e-99 PF01545: Cation_efflux" amino acids 18 to 210 (193 residues), 170.9 bits, see alignment E=1.5e-54

Best Hits

Swiss-Prot: 73% identical to ZITB_PECAS: Zinc transporter ZitB (zitB) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K03295, cation efflux system protein, CDF family (inferred from 100% identity to ddd:Dda3937_03986)

MetaCyc: 67% identical to Zn2+/Cd2+/Ni2+/Cu2+ exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-200

Predicted SEED Role

"Zinc transporter ZitB" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SFQ1 at UniProt or InterPro

Protein Sequence (311 amino acids)

>DDA3937_RS06555 CDF family zinc transporter ZitB (Dickeya dadantii 3937)
MAHSHPANQAEHDSIKRLKLAFVITATFMLAEAVGGVLSGSLALLADAGHMLTDAVALLV
ALLAVRFAQRKPTVRHTFGYVRLTTLAAFVNAIALLAITGFIVWEAAQRFYTPQPIASTP
MLLIAVGGLIANLVALWLLHRGSGEKNINVRAAALHVMGDLLGSVGAIGAALIIMFTGWT
PIDPILSVLVSILVLRSAWRLMKESVHELLEGTPTRINVDQLKRKLTADIPEIRNVHHVH
LWQVGEKPLMTLHAQVIPPHDHDALLQRIQHYLLDHYQIAHTTIQIEYQPCDDDHCDIQY
QAGDQPHSHSH