Protein Info for DDA3937_RS06550 in Dickeya dadantii 3937

Annotation: nicotinamide riboside transporter PnuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 transmembrane" amino acids 22 to 40 (19 residues), see Phobius details amino acids 47 to 65 (19 residues), see Phobius details amino acids 71 to 88 (18 residues), see Phobius details amino acids 109 to 127 (19 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 185 to 203 (19 residues), see Phobius details amino acids 209 to 226 (18 residues), see Phobius details TIGR01528: nicotinamide mononucleotide transporter PnuC" amino acids 22 to 230 (209 residues), 191.2 bits, see alignment E=8.5e-61 PF04973: NMN_transporter" amino acids 23 to 227 (205 residues), 168.6 bits, see alignment E=6.7e-54

Best Hits

Swiss-Prot: 70% identical to PNUC_SALTY: Nicotinamide riboside transporter PnuC (pnuC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03811, nicotinamide mononucleotide transporter (inferred from 100% identity to ddd:Dda3937_03985)

MetaCyc: 68% identical to nicotinamide riboside transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-481

Predicted SEED Role

"Ribosyl nicotinamide transporter, PnuC-like" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation or PnuC-like transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SFQ0 at UniProt or InterPro

Protein Sequence (241 amino acids)

>DDA3937_RS06550 nicotinamide riboside transporter PnuC (Dickeya dadantii 3937)
MDFFSTSNILVHIPLGDNGYDLSWVEALGTLSGLVCIWLASLERTANYLFGLINVSLFAL
IFFQIQLYASLLLQIFFIAANVYGWYAWSRIADEQEAELRVRWLSRRQALWWGAGCVIAT
VLMSRYIDPFFALLSRIAVTLMQAVGLDVTMPTLQPDAFPFWDSAMTVLSVAAMLLMTRK
YVENWLLWVVIDIISVVIFAYQGVYVMSLQYMVLTLIALNGSWLWIKGARDNHSRPLARA
L