Protein Info for DDA3937_RS06355 in Dickeya dadantii 3937

Annotation: alpha-D-glucose phosphate-specific phosphoglucomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01132: phosphoglucomutase, alpha-D-glucose phosphate-specific
  • amino acids 1 to 543 (543 residues), 1022.9 bits, E=0
• PF02878: PGM_PMM_I
  • amino acids 41 to 179 (139 residues), 108.5 bits, E=4.4e-35
• PF02879: PGM_PMM_II
  • amino acids 209 to 317 (109 residues), 58.2 bits, E=2.1e-19
• PF02880: PGM_PMM_III
  • amino acids 320 to 439 (120 residues), 102.4 bits, E=3.3e-33
• PF00408: PGM_PMM_IV
  • amino acids 489 to 536 (48 residues), 25.4 bits, 2.4e-09

Best Hits

Swiss-Prot: 85% identical to PGM_ECOLI: Phosphoglucomutase (pgm) from Escherichia coli (strain K12)

KEGG orthology group: K01835, phosphoglucomutase [EC: 5.4.2.2] (inferred from 100% identity to ddd:Dda3937_01555)

MetaCyc: 86% identical to phosphoglucomutase (Yersinia enterocolitica (type O:8))
Phosphoglucomutase. [EC: 5.4.2.2]

Predicted SEED Role

"Phosphoglucomutase (EC 5.4.2.2)" (EC 5.4.2.2)

MetaCyc Pathways

• superpathway of anaerobic sucrose degradation (17/19 steps found)
• colanic acid building blocks biosynthesis (11/11 steps found)
• glycogen degradation I (8/8 steps found)
• O-antigen building blocks biosynthesis (E. coli) (10/11 steps found)
• D-galactose degradation I (Leloir pathway) (5/5 steps found)
• dTDP-β-L-rhamnose biosynthesis (5/5 steps found)
• glycogen biosynthesis I (from ADP-D-Glucose) (4/4 steps found)
• UDP-α-D-glucose biosynthesis (2/2 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• glucose and glucose-1-phosphate degradation (4/5 steps found)
• sucrose degradation II (sucrose synthase) (4/5 steps found)
• sucrose biosynthesis II (6/8 steps found)
• starch degradation V (3/4 steps found)
• sucrose degradation IV (sucrose phosphorylase) (3/4 steps found)
• GDP-α-D-glucose biosynthesis (2/3 steps found)
• trehalose degradation V (2/3 steps found)
• glycogen degradation II (4/6 steps found)
• superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis (4/6 steps found)
• glucosylglycerol biosynthesis (3/5 steps found)
• starch degradation III (2/4 steps found)
• starch biosynthesis (6/10 steps found)
• chitin biosynthesis (5/9 steps found)
• CDP-6-deoxy-D-gulose biosynthesis (1/5 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (2/8 steps found)
• superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (7/19 steps found)
• streptomycin biosynthesis (2/18 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (12/33 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Glycolysis / Gluconeogenesis
• Nucleotide sugars metabolism
• Pentose phosphate pathway
• Starch and sucrose metabolism
• Streptomycin biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.2

Sequence Analysis Tools

See E0SEX3 at UniProt or InterPro

Protein Sequence (547 amino acids)

>DDA3937_RS06355 alpha-D-glucose phosphate-specific phosphoglucomutase (Dickeya dadantii 3937)
MANHPRAGQPTRQSDLINVAQLTSQYYVLRPDVTNPAQSVKFGTSGHRGCAARHSFNEAH
ILAIAQAIAEERRRQGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQQDNGFTPT
PAVSNAILVHNRQGGALADGIVITPSHNPPEDGGIKYNPPNGGPADTNLTSVIEKRANAL
LADDLRDVKRQSLDKARQSGHLHERDLVEPYVEALGEVVDMAAIQRAGLKLGVDPLGGSG
IAYWQRIAERYQLDLTLVNDAVDQTFRFMTLDHDGVIRMDCSSVSAMAGLLALRDKFDLA
FANDPDYDRHGIVTPAGLMNPNHYLAVAIDYLFRHRPQWSESVAVGKTLVSSAMIDRVVA
DLGRKLVEVPVGFKWFVDGLFDGTLGFGGEESAGASFLRFDGKPWSTDKDGIILCLLAAE
ITAVTGKNPQQHYDALAARFGAPSYNRLQAPATHAQKAALSKLSPEMVSASTLAGDPITA
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEEAYKIYCESFLGAEHREKIEKEAVEIVG
AVLSSAK