Protein Info for DDA3937_RS05795 in Dickeya dadantii 3937

Annotation: molecular chaperone HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 PF13589: HATPase_c_3" amino acids 26 to 165 (140 residues), 41.5 bits, see alignment E=2e-14 PF02518: HATPase_c" amino acids 28 to 182 (155 residues), 34.2 bits, see alignment E=4.7e-12 PF00183: HSP90" amino acids 219 to 626 (408 residues), 424.9 bits, see alignment E=8.9e-131

Best Hits

Swiss-Prot: 89% identical to HTPG_PECAS: Chaperone protein HtpG (htpG) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 100% identity to ddd:Dda3937_03288)

MetaCyc: 85% identical to chaperone protein HtpG (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SDX0 at UniProt or InterPro

Protein Sequence (627 amino acids)

>DDA3937_RS05795 molecular chaperone HtpG (Dickeya dadantii 3937)
MKGQETRGFQSEVKQLLHLMIHSLYSNKEVFLRELISNASDAADKLRFRALSAPDLYEGD
GELRVRVSIDKEQRTLTISDNGIGMSRDDVIDNLGTIAKSGTKAFLESLGSDQAKDSQLI
GQFGVGFYSAFIVADKVTVKTRVAGASADQGVFWESAGEGEYTIADIARAERGTEITLHL
REGEDEFLDNWRVRSVISKYSDHIALPVEIESRTESEEEGGEETVTWEKINKAQALWTRS
KSDISDDEYHEFYKHIAHDFTEPLSWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGL
KLYVQRVFIMDDAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDNRVTQSLRTALTKRVL
QMLEKLAKDDGEKYQTFWRQFGLVLKEGPAEDGGNRETIAKLLRFATTHNDSDEQSVSLD
DYISRMVEGQDKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFDG
KSFQSVSKADESLDKLADEADESQKEAEKALEPFVERVKTLLGERVKEVRLTHRLTDTPA
IVTTDANDMSTQMAKLFAAAGQQAPEVKYIFELNPEHALVKRAAETQDDTQFGEWVELLL
DQALFAERGTLEDPNQFIRRMNQLLTA