Protein Info for DDA3937_RS05310 in Dickeya dadantii 3937

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 77 to 234 (158 residues), 129.7 bits, see alignment E=4.3e-42 PF00990: GGDEF" amino acids 81 to 231 (151 residues), 125.5 bits, see alignment E=8.7e-41

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01915)

Predicted SEED Role

"FIG066100: Diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SCG9 at UniProt or InterPro

Protein Sequence (241 amino acids)

>DDA3937_RS05310 GGDEF domain-containing protein (Dickeya dadantii 3937)
MSSYELFTPEYDILLSARNIAAQADMPAEVYRESLIMLAEHYQRLVRETHRLITRSDRAE
RELTRLNTQLHQLAVELEYKATHDPLTDVFNRSAIIDLVDHALEQDQAALIVLDIDHFKQ
VNDAYGHPTGDAVICSLIARIRDVLQGKGSIGRVGGEEFTILLDGYTLMAAVDVAEHIHA
SLNGAALEALPQQKVTASFGVSWAPPRTGFDTLYSTADTALYRAKHQGRNRVEYMPIDAV
S