Protein Info for DDA3937_RS05105 in Dickeya dadantii 3937

Annotation: bifunctional uridylyltransferase/uridylyl-removing protein GlnD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 893 TIGR01693: protein-P-II uridylyltransferase" amino acids 48 to 885 (838 residues), 1007.2 bits, see alignment E=3.5e-307 PF01909: NTP_transf_2" amino acids 84 to 117 (34 residues), 26.5 bits, see alignment (E = 1.8e-09) PF08335: GlnD_UR_UTase" amino acids 194 to 332 (139 residues), 155.2 bits, see alignment E=2.8e-49 PF01966: HD" amino acids 469 to 577 (109 residues), 45 bits, see alignment E=3e-15 PF01842: ACT" amino acids 710 to 761 (52 residues), 33.4 bits, see alignment 7.5e-12 amino acids 819 to 865 (47 residues), 30.3 bits, see alignment 7.2e-11

Best Hits

Swiss-Prot: 89% identical to GLND_PECCP: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 100% identity to ddd:Dda3937_00877)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SCC7 at UniProt or InterPro

Protein Sequence (893 amino acids)

>DDA3937_RS05105 bifunctional uridylyltransferase/uridylyl-removing protein GlnD (Dickeya dadantii 3937)
MIDRDLPHDTPGSTTTVHPAPASPLTFTDDMLKCQTLKTHLEQFQSWLTEEFKAGVSAEA
LIDTRTLFIDHLMQRLWRFYGFERVPQTALVAVGGYGRGELHPLSDIDLLVLSQHKLTDA
QSQAIGTFITLLWDLRLEVGHSVRTLDECLEEGRADISVATNLIESRMICGDVALFLMLQ
KHIFSDAFWPSETFFPAKIAEQRERHQRYHSTSYNLEPDIKSSPGGLRDIHTLLWVARRH
FGATSLNEMVGFGFLTEAERNELNECQSFLWRIRFALHSILPRYDNRLLFDRQLNVAQLL
QYQGEGNAPVEHMMKDFYRMTRRVGELNQMLLQLFDEAILALDASEKPRPLDEEFQLRGQ
LIDLRDETLFEHKPEAIIRMFYLMVRNQEITGIYSTTLRHLRHARRHLTQPLCTIPEARN
LFMNILRHPRAVSRALLPMHTHSVLWAYMPLWGNIVGQMQFDLFHAYTVDEHTIRVLLKL
ESFTEEATRASHPLCVELYPRLPQPELLLLAALFHDIAKGRGGDHSELGAKDALEFAVLH
GLNSRETQLVAWLVRCHLLMSVTAQRRDIQDPAVIQQFAEQVQSETRLRYLLNLTVADIC
ATNETLWNSWKQSLLRELYFATEKQLRRGMQNSPDLRERVRHHRLQALALLRMDNIDEEA
LHHIWSRCRADYFLRHSPNQLAWHARHLLEHDVNKPMVLISHQASRGGTEIFIWSPDRPY
LFAAVAGELDRRNLSVHDAQIFTSRDGMAMDTFIVLEPDGSPLAPDRHDMIRHAIEQALT
QRDYQHPRVRRPSSRLRHFSVPTEVGFLPTHTDRRSYMELIALDQPGLLARVGEVFADLN
LSLHGARISTIGERVEDLFILADSERRALSPELRLKLQQRLTEALDPNDKVAS