Protein Info for DDA3937_RS04800 in Dickeya dadantii 3937

Annotation: TolC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 488 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02321: OEP" amino acids 49 to 268 (220 residues), 57.6 bits, see alignment E=7.7e-20 amino acids 313 to 476 (164 residues), 78.4 bits, see alignment E=3.2e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01488)

Predicted SEED Role

"Outer membrane efflux family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SBR2 at UniProt or InterPro

Protein Sequence (488 amino acids)

>DDA3937_RS04800 TolC family protein (Dickeya dadantii 3937)
MIKTVALVLLLLVGLDASAALTDRLLPSQATRAGSSTLSPNAQIIDLTLSDAIYLGLRDN
RAIRSAYLDRVAQKFDLLVAEDRFTPKLVLSGSYLAARNQDDRYRQGEIAPTTTLLTPYG
TRVSLAWTHRSTQADEAGRTRNDGATITVIQPLLRGAGKEIATAPVRLAKLSEQINRLTL
KATVARTITQIIMAYRALLQTQEQLNIADEALARSRQLLEVNRSLIAAGRMAEFEIIQTE
ADVATQELSREEALNQLDVSRLALLQLLALDLRTPVRATERLQASRVDVSPAAALSQAEA
LQPAYLTQLIVDKQADINLAVARNDRLWDVSLVGGTNQLRDRSSTVGSSRNWENYVGVQV
DIPIGDMSQQQAEVQARVNVQNQRIQLAETRQQLERDVANAVRDISTRWRQFEIAQRARD
LSRRKLEIEREKLTAGRSSNFQVLSFETDLRNAENARLSALITYLNTQADLDQTLGTTLQ
SWDISLND