Protein Info for DDA3937_RS04555 in Dickeya dadantii 3937
Annotation: DNA-3-methyladenine glycosylase 2 family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 50% identical to MAG1_SCHPO: DNA-3-methyladenine glycosylase 1 (mag1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)
KEGG orthology group: K01247, DNA-3-methyladenine glycosylase II [EC: 3.2.2.21] (inferred from 100% identity to ddd:Dda3937_01441)Predicted SEED Role
"DNA-3-methyladenine glycosylase II (EC 3.2.2.21)" in subsystem DNA Repair Base Excision (EC 3.2.2.21)
Isozymes
Compare fitness of predicted isozymes for: 3.2.2.21
Use Curated BLAST to search for 3.2.2.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E0SB63 at UniProt or InterPro
Protein Sequence (224 amino acids)
>DDA3937_RS04555 DNA-3-methyladenine glycosylase 2 family protein (Dickeya dadantii 3937) MTTSPLPFDEPQALAHLAAIDAHWARLIDGVGHIRFESRPAREPYDALIRAVASQQLSNR AAAAIIGKLQQRFAVGENGFPSADQLATCEPEVLRQCGFSARKIDTVKGIAQGVQNGLVP SRAEAEHLDDETLIERLCTLKGIGRWTVEMLLISTLERMDIMPVDDLGIKQGFRYLYRLP QDPTRKAMLEMSEACRPYRTLAAWYLWRIPHMPDYAEYRASLRQ