Protein Info for DDA3937_RS03995 in Dickeya dadantii 3937

Annotation: P-type conjugative transfer ATPase TrbB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 TIGR02782: P-type conjugative transfer ATPase TrbB" amino acids 2 to 297 (296 residues), 406.5 bits, see alignment E=3.7e-126 PF00437: T2SSE" amino acids 91 to 273 (183 residues), 117.8 bits, see alignment E=4.5e-38 PF10412: TrwB_AAD_bind" amino acids 123 to 168 (46 residues), 22.7 bits, see alignment 4.2e-09

Best Hits

Swiss-Prot: 48% identical to TRBB_SINFN: Probable conjugal transfer protein TrbB (trbB) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K03196, type IV secretion system protein VirB11 (inferred from 100% identity to ddd:Dda3937_01738)

Predicted SEED Role

"Conjugative transfer protein TrbB" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SAI5 at UniProt or InterPro

Protein Sequence (317 amino acids)

>DDA3937_RS03995 P-type conjugative transfer ATPase TrbB (Dickeya dadantii 3937)
MLYTALGPLIAAALDDPDVVEIMLNPDCTLWVDRLSTGLAPLGGGLSAAEGERIIRLVAA
HVGTEVHRHRPLLTAELPETGERFEGILPPAAPGPAFALRKRAVGVIPLTRYVADGMMTA
AQAGVLRQAVRERHNILIAGGTSTGKTTLANALLAEIAETGDRVLVLEDTVELQCVARDQ
VPLRTRPGVVSMAELVRTTLRLRPDRVIVGEVRGGEALDLLKVWGTGHPGGIATLHAGSA
LGALLRLEQLILEVAITPPRALIADTIHLIVHLTGRGQARRIASLVRVTGFDGTHYQLSN
LGSPGPAVSTPLPGGSS