Protein Info for DDA3937_RS03725 in Dickeya dadantii 3937

Annotation: 5-dehydro-2-deoxygluconokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 661 TIGR04382: 5-dehydro-2-deoxygluconokinase" amino acids 6 to 331 (326 residues), 429.7 bits, see alignment E=3.2e-133 PF00294: PfkB" amino acids 8 to 323 (316 residues), 152.9 bits, see alignment E=1.3e-48 PF09863: DUF2090" amino acids 326 to 410 (85 residues), 97.4 bits, see alignment E=8.8e-32 amino acids 432 to 660 (229 residues), 381.9 bits, see alignment E=2.2e-118

Best Hits

KEGG orthology group: K03338, 5-dehydro-2-deoxygluconokinase [EC: 2.7.1.92] (inferred from 98% identity to ddd:Dda3937_01208)

Predicted SEED Role

"5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain" in subsystem Inositol catabolism (EC 2.7.1.92)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SMN5 at UniProt or InterPro

Protein Sequence (661 amino acids)

>DDA3937_RS03725 5-dehydro-2-deoxygluconokinase (Dickeya dadantii 3937)
MSTQKQFDVICMGRVAVDLYGQQIGSRLEDMGSFAKYLGGSSGNVAYGTARQGLRSSMLA
RVGDEHMGRFLREELQQVGCDTSHLITDPTRLTALVLLGIKDRETFPLIFYRDNCADMAI
TPEDVSEDYIASSRCLAITGTHLSHPNTREAVLTALRYARRHGVKTVLDIDYRPVLWGLT
SPGDGETRFIESAAVTAQLQQVLNLFDLIVGTEEEFHIAGGSTDTLQALRQVRAHTAAEL
VCKRGPLGCSVFTGDIPASLDEGITVKGVRVEVLNVLGAGDAFMSGLLRGYLSGEGWEKA
CAYANACGALVVSRHGCAPAMPSRIELDNYLARAHAVPRPDLDPELNHLHRVTTRRQRWE
ELCVIAFDHRIQLEEMALACGAERSRIPALKQLILQASQQAAQQAGLLGVTGSPDKAGLT
AGRAGLTPGKAGLTPGKAGLLCDGTFGQDALNAITGQGWWIGRPIELPGSRPLALEHGNI
GSQLVNWPLEHIVKCLVFFHPEDDSPLRLAQERQVTEVYRACCQSGHELLLEVILPADMP
RSDDLYLRAIQRFYNLGIRPDWWKLPPLSADGWRRLEHLLAERDPYCRGVVILGLDAPIE
TLRQGFNAAAGQSVVKGFAVGRTLFAQPAQQWLRGDINDERLIADVKNNYLQLIALWRQR
G