Protein Info for DDA3937_RS03705 in Dickeya dadantii 3937

Annotation: substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 27 to 280 (254 residues), 195.1 bits, see alignment E=2.5e-61 PF00532: Peripla_BP_1" amino acids 27 to 275 (249 residues), 63.1 bits, see alignment E=4.5e-21 PF13377: Peripla_BP_3" amino acids 148 to 283 (136 residues), 44.7 bits, see alignment E=2.4e-15

Best Hits

Swiss-Prot: 34% identical to RBSB_SALTI: Ribose import binding protein RbsB (rbsB) from Salmonella typhi

KEGG orthology group: K10439, ribose transport system substrate-binding protein (inferred from 100% identity to ddd:Dda3937_01204)

MetaCyc: 33% identical to ribose ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-28-RXN

Predicted SEED Role

"Inositol transport system sugar-binding protein" in subsystem Inositol catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SMN1 at UniProt or InterPro

Protein Sequence (312 amino acids)

>DDA3937_RS03705 substrate-binding domain-containing protein (Dickeya dadantii 3937)
MKKITIMAAAMAFTMSSGLAQAQNEQIVFSTPNLAMPFEVHMQRTAVKAAKELGVNLQVL
DSQGSSPKQVADLENAITRGAQGFVVSPNDVNAVSGAVTEIQDAKLPVVTLDRSVKTDKK
VPHFGANNYKGGQAIADFVKARFPNGADIVLLTGQPGSSSNIERTQGIRDSLKAGGSKYR
LVADQTGNWMRSEGMRIVESVLPSLPKRPQVILSANDDMALGAIEALQSQGLKPGEVMVT
GFDAVPEALARVRDGWLSVTADQRPGYAVTQAMTQLTNNIRTKSPITGADYPPTMITKDN
LNDAERIGEAGK