Protein Info for DDA3937_RS03555 in Dickeya dadantii 3937

Annotation: DHA2 family efflux MFS transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 172 to 195 (24 residues), see Phobius details amino acids 207 to 225 (19 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 274 to 299 (26 residues), see Phobius details amino acids 312 to 329 (18 residues), see Phobius details amino acids 341 to 359 (19 residues), see Phobius details amino acids 365 to 386 (22 residues), see Phobius details amino acids 497 to 515 (19 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 19 to 515 (497 residues), 336.7 bits, see alignment E=1.2e-104 PF07690: MFS_1" amino acids 23 to 417 (395 residues), 174 bits, see alignment E=4.4e-55 PF00083: Sugar_tr" amino acids 56 to 189 (134 residues), 25.3 bits, see alignment E=6.9e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01172)

Predicted SEED Role

"Multidrug resistance protein B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SMJ8 at UniProt or InterPro

Protein Sequence (534 amino acids)

>DDA3937_RS03555 DHA2 family efflux MFS transporter permease subunit (Dickeya dadantii 3937)
MSPIEAQAARFGHHYRWLATVTIMLGTIATTATATIVNVAMRDIMGAFGMGQDQAQWLST
AFLASMTATMLITAWTLERFGYRATYVGSLAVFIAGSLLGTFSQSSAEVILARILQGGAS
GVIQPLAMIIISQVFPVSERGKAMGIYGVGVVLAPALGPAAGGLMVDQLDWRAVFMVVVP
FCLAGIAAALVILPAKSAQTDSTPRRFDTLGFILLVTALTSLLAGLSNGQREGWESFFIL
CLLTTAVIATLAFIIREFTTPYPLLSLRVFANPAFTSGCIVAFALGAGIYGSTYIIPLFV
QSIQGYTPTRSGLLLMPAGLALGMVFPLAGSLSDKLKPHQLVIAGLLLFGLSCWLSSAAD
TDTPFWTMAWWIVIGRVGLGVMLPAMNAGALRALPHAQLAQGAGSLNFVRQLGGAMGVNL
LSVFIERRATFHGQMLAQSLTLDNIRSTDAIRQLSLLFGHGGNPLGDPLNTSINPGIMTY
LESVLAPKAQMFAYQDGFFMVAMFFFLAILPAWFIRPRPVLNPTSPPGAAKTPA