Protein Info for DDA3937_RS02170 in Dickeya dadantii 3937
Annotation: D-threitol dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01335)Predicted SEED Role
"2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 1.1.1.125)
MetaCyc Pathways
- 2-deoxy-D-glucose 6-phosphate degradation (3/4 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.1.1.125
Use Curated BLAST to search for 1.1.1.125
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E0SJ25 at UniProt or InterPro
Protein Sequence (267 amino acids)
>DDA3937_RS02170 D-threitol dehydrogenase (Dickeya dadantii 3937) MSHDNEYDVNLRYGVDTDLSLSDKVAVVTGGLGGIAMASNEMLLAKGARLALLYPAFERD KAAQAAERFDPTRVLLVECDVTTPAEVERAFAAVEAHYGRIDILINCAGYVMLQPVLETD FDEWQKQIAVNLTGPFLCSQAAARHMVAAGHGGKIINIASQAASIAIDNHVAYTSAKAGL LGMTKVMAKELAPHRINVNTLSPTVVLTPMGEKAWRGEKGEAMKKLIPLGRFAYTDEIAA AVLFFASNGSDMITGADLMIDGGFTIW