Protein Info for DDA3937_RS01730 in Dickeya dadantii 3937

Annotation: glutathionylspermidine synthase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03738: GSP_synth
  • amino acids 12 to 384 (373 residues), 547 bits, E=1.2e-168

Best Hits

Swiss-Prot: 73% identical to YGIC_ECO57: Putative acid--amine ligase YgiC (ygiC) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_00724)

MetaCyc: 73% identical to peptide--spermidine ligase YgiC (Escherichia coli K-12 substr. MG1655)
6.3.1.-

Predicted SEED Role

"Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1" in subsystem Glutathionylspermidine and Trypanothione (EC 6.3.1.8)

MetaCyc Pathways

• glutathionylspermidine biosynthesis (1/1 steps found)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.1.8

Sequence Analysis Tools

See E0SI48 at UniProt or InterPro

Protein Sequence (386 amino acids)

>DDA3937_RS01730 glutathionylspermidine synthase family protein (Dickeya dadantii 3937)
MKRIAINERPNWQEKAAEYGFRFHTMYGEPYWCEDAYYQFTLAQIEELEDATAELNQMCL
QVVDKVVNSEALLTKFRIPRHTWDFVRSSWLSRQPALYARLDLAYDGKNPAKLLENNADT
PTSLYESAFFQWIWLEDQINAGRLPQHADQYNSLQEQLIERFEYLRTHHGFGNMHFTCCR
DTDEDRGTVQYLQDCAQEAGVPSQFLYIDEIGLGDRGQFTDLQDNTIGNLFKLYPWEFML
RETFSTKLADAGVRWLEPGWKSVVSNKALLPMLWQMFPNHPNLLPAYFTEDNPPAMSDYV
VKPLFSREGANIRIYRQGQQVAAVDGPYGEEGSIVQQFHPLPRFNDSYTLIGSWLVGDNP
CGIGLREDRELITQDLSRLYPHIILD