Protein Info for DDA3937_RS01615 in Dickeya dadantii 3937

Annotation: cell division protein ZapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF03969: AFG1_ATPase" amino acids 4 to 372 (369 residues), 494.9 bits, see alignment E=6.8e-153

Best Hits

Swiss-Prot: 65% identical to ZAPE_ECO57: Cell division protein ZapE (zapE) from Escherichia coli O157:H7

KEGG orthology group: K06916, (no description) (inferred from 100% identity to ddd:Dda3937_04446)

Predicted SEED Role

"ATPase, AFG1 family" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SHD9 at UniProt or InterPro

Protein Sequence (376 amino acids)

>DDA3937_RS01615 cell division protein ZapE (Dickeya dadantii 3937)
MQRTTPLALYQQALAAQTYQPDEVQHQTVVRLNAIHQTLTEQVWAPAESSAPGLMAKWRT
WLGQKEKSPSPVQGLYMWGGVGRGKTWLMDLFFHSLPSERKLRLHFHRFMLRVHEELNQL
QGQENPLEKVADGFKAQTDILCFDEFFVSDITDAMLLAELLRALFSRGIALVATSNIPPD
ELYRNGLQRARFLPAIELIKQHCGVLNVDAGIDYRLRTLTQAHLYLTPSNADTDAEMQAM
FRCLSGRDFSQPGPVLEINHRPLTTLSAGDGVLAVDFATLCLEARSQNDYIALSRLYHTV
LLHHVPVMEVKDENAARRFLALVDEFYERRVKLIMSAQATMFEIYQGEHLKFEYQRCLSR
LQEMQSEEYLRQPHLP