Protein Info for DDA3937_RS00420 in Dickeya dadantii 3937

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 PF00532: Peripla_BP_1" amino acids 64 to 246 (183 residues), 60.8 bits, see alignment E=2.3e-20 PF13407: Peripla_BP_4" amino acids 67 to 313 (247 residues), 52.4 bits, see alignment E=9e-18 PF13377: Peripla_BP_3" amino acids 188 to 329 (142 residues), 42.9 bits, see alignment E=8.9e-15

Best Hits

KEGG orthology group: K03435, LacI family transcriptional regulator, fructose operon transcriptional repressor (inferred from 100% identity to ddd:Dda3937_02532)

Predicted SEED Role

"transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SEQ1 at UniProt or InterPro

Protein Sequence (334 amino acids)

>DDA3937_RS00420 LacI family DNA-binding transcriptional regulator (Dickeya dadantii 3937)
MAKTVEQIASALKLSVTTVRLVLNGKAEQYRISAKTQQRIHQYVTEYGYTVNHVARSLKL
NKTETLGLIVPRLSNLFFSTLAEKLETRCREVGYQLMISCSYSDPQYENRLVEALLQRNV
DGLFVVPSSLQAAQHHAKVVKKPLVLLDRDFGIDQLPLVMSDNLQGGAALTEAMLAAQPA
APLFFMAGDVQQSAIRDRLRGYRQSVQQAGLTPAVLEASHNRREDGMLMMEQFLRQHDAP
PPAFIASSLPVLEGMLSVVRERYGYIPAHINIGTFDEHAMLGFLPNTLWSMRQNEDAWTE
QAFAAMQQALNGEAQPHKAVIPMTLIHRRQAERH