Protein Info for DDA3937_RS00165 in Dickeya dadantii 3937

Annotation: uracil-xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 transmembrane" amino acids 35 to 61 (27 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 127 to 146 (20 residues), see Phobius details amino acids 157 to 181 (25 residues), see Phobius details amino acids 193 to 211 (19 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 259 to 279 (21 residues), see Phobius details amino acids 349 to 371 (23 residues), see Phobius details amino acids 378 to 398 (21 residues), see Phobius details amino acids 407 to 428 (22 residues), see Phobius details amino acids 437 to 457 (21 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 28 to 456 (429 residues), 463.5 bits, see alignment E=6.9e-143 PF00860: Xan_ur_permease" amino acids 33 to 425 (393 residues), 369.9 bits, see alignment E=6.6e-115 TIGR03173: xanthine permease" amino acids 38 to 458 (421 residues), 418.9 bits, see alignment E=2e-129

Best Hits

Swiss-Prot: 88% identical to XANP_SHIFL: Xanthine permease XanP (xanP) from Shigella flexneri

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_01124)

MetaCyc: 88% identical to xanthine:H+ symporter XanP (Escherichia coli K-12 substr. MG1655)
RXN-5076

Predicted SEED Role

"Xanthine-uracil permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SDW0 at UniProt or InterPro

Protein Sequence (462 amino acids)

>DDA3937_RS00165 uracil-xanthine permease (Dickeya dadantii 3937)
MSLSTTELPQADAATPANSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQAL
GLPAQDTQHIISMSLFASGLASILQIKTWGPVGSGLLSIQGTSFNFVTPLIMGGMALKNG
GADVPTMMAALFGTLMVASCTEILLSRVLHLARRIITPLVSGIVVMIIGLSLIQVGLTSI
GGGFAAMSNHTFGAPKNLLLAAIVLAVIIILNRQRNPYLRVASLVIAMAVGYLAAWLMGM
LPESAGTSSHALINVPTPLYYGLGFDWNLLIPLMLVFMVTSLETIGDITATSDVSEQPVS
GPLYMKRLKGGVLANGLNSCLSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIV
LGLFPAVSGFVQHIPEPVLGGATIVMFGTIAASGVRIVSREPLNRRAIMIIALSLAVGLG
VSQQPLILQFAPEWLKTLLSSGIAAGGITAIVLNLVFPQEKE