Protein Info for COO64_RS26260 in Pseudomonas sp. SVBP6

Annotation: MDR family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 31 to 49 (19 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 147 to 165 (19 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 212 to 230 (19 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 286 to 305 (20 residues), see Phobius details amino acids 317 to 334 (18 residues), see Phobius details amino acids 340 to 363 (24 residues), see Phobius details amino acids 386 to 407 (22 residues), see Phobius details amino acids 439 to 458 (20 residues), see Phobius details PF07690: MFS_1" amino acids 1 to 392 (392 residues), 190.9 bits, see alignment E=6.1e-60 TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 1 to 401 (401 residues), 236.7 bits, see alignment E=2.4e-74 PF00083: Sugar_tr" amino acids 30 to 159 (130 residues), 56.7 bits, see alignment E=4.1e-19 PF06609: TRI12" amino acids 38 to 394 (357 residues), 52.1 bits, see alignment E=7.9e-18 PF12832: MFS_1_like" amino acids 50 to 151 (102 residues), 25.7 bits, see alignment E=1.2e-09

Best Hits

KEGG orthology group: None (inferred from 79% identity to pen:PSEEN4357)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>COO64_RS26260 MDR family MFS transporter (Pseudomonas sp. SVBP6)
MLAIFLGALDQTIVAVSMPAISAQFNDVGLLAWVISGYMVAMTVAVPIYGKLGDLYGRRR
MILTGTALFTLASIFCALAQNMEQLVLARVLQGIGAGGMVSVSQAIIGDFVPPRERGRYQ
GYFSSMYALASVAGPVLGGMLTEYLSWRWVFWLNLPLGLTAWWVTRRALRSLLVPTHKAQ
VDYLGAALLILGLGSLLLGITLIGQGQPWDSAQVASLLGCALIGLLLFVLHEQRVAEPLL
PLKLFANRTATLCWCTIFFTSFQAISLTMLMPLRYQSITGAGADSAALHLLPLAIGLPIG
AYCGGRLTSLTGRYKPQILGGALLMPFAIVGMAFSPPQAAWFSGMFMVLTGIASGLQFPT
SLVATQSAVEPRDIGVATSTTNLFRSLGGAMGVAIMSTLLLAMLAQGGLSLAGDALLGSL
QAGEPTAAMQAELLLTFRNLLLGSATVSLLGLTAALALPDRQLRGRQ