Protein Info for COO64_RS20005 in Pseudomonas sp. SVBP6

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 632 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 58 to 80 (23 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 149 to 167 (19 residues), see Phobius details amino acids 176 to 198 (23 residues), see Phobius details amino acids 215 to 240 (26 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 295 to 319 (25 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 374 to 399 (26 residues), see Phobius details amino acids 405 to 423 (19 residues), see Phobius details amino acids 430 to 450 (21 residues), see Phobius details PF02705: K_trans" amino acids 21 to 472 (452 residues), 615.7 bits, see alignment E=4.1e-189 PF22776: K_trans_C" amino acids 485 to 632 (148 residues), 173.6 bits, see alignment E=2.6e-55

Best Hits

Swiss-Prot: 88% identical to KUP_PSEE4: Probable potassium transport system protein kup (kup) from Pseudomonas entomophila (strain L48)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 88% identity to pen:PSEEN4112)

MetaCyc: 51% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (632 amino acids)

>COO64_RS20005 potassium transporter Kup (Pseudomonas sp. SVBP6)
MVQASSQADSGHSVAKPLSLLVAAVGVVYGDIGTSPLYTLKEVFSGGYGVPVNHDGVLGI
LGLIFWSLIWVVTIKYVVFILRADNQGEGGIMALTALARRASTPYPKLKALMVGCGLIGA
ALFYGDSMITPAISVLSAVEGLELAFDGIDHWVIPVALIVLVALFLIQKHGTARIGILFG
PVMVTWFVVLGALGVHGIAQSPEVLKAFNPVWAVRFFIVHPGMGVAILGAVVLALTGAEA
LYADMGHFGRKPIARAWFALVLPALVLNYFGQGALLLQNPEAARNPFYLLAPNWALIPLV
GLSTLATVIASQAVISGAFSLTRQAIQLGYVPRMQIQHTSSDEQGQIYIGAVNWSLMVGV
ILLVLGFESSGALASAYGVAVTGTMLMTTLLVSTVMLLLWKWPPLLAVPILLGFLFVDGL
FFAANVPKIVQGGAFPVLAGIVLFVLMTTWKRGKQILVERLDEGSLPLPLFISSIRVQPP
HRVEGTAVFLTARADAVPHALLHNMLHNQVLHSQVVLLTVVSEDTPRVPAQQRFEVEAYG
EGFYRVLLHFGFMDEPDVPAALKLCHLEGLDFSPMRTTYFLSRETVIASRLVGMARWRGL
LFAFLLKNANGNLRFFNLPLNRVIELGTQVEI