Protein Info for COO64_RS05345 in Pseudomonas sp. SVBP6

Annotation: OmpA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF05736: OprF" amino acids 1 to 180 (180 residues), 259.2 bits, see alignment E=3.1e-81 PF13505: OMP_b-brl" amino acids 14 to 177 (164 residues), 47.5 bits, see alignment E=3.6e-16 PF00691: OmpA" amino acids 239 to 334 (96 residues), 84.1 bits, see alignment E=1.1e-27

Best Hits

Swiss-Prot: 79% identical to PORF_PSESY: Outer membrane porin F (oprF) from Pseudomonas syringae pv. syringae

KEGG orthology group: K03286, OmpA-OmpF porin, OOP family (inferred from 96% identity to ppw:PputW619_1607)

Predicted SEED Role

"Major porin and structural outer membrane porin OprF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (345 amino acids)

>COO64_RS05345 OmpA family protein (Pseudomonas sp. SVBP6)
MKLKNTLGLAIGSLVAATSFGALAQGQGAVEIEGNVTKQYYDSERNFKNTGTNPGVRLGY
FLTDDLSLDLGYNETHNARGEVFNKDIKGSKAKLDATYHFGTVGDALRPYVSAGFAHESL
GQATRGGRDHSTFANVGAGAKWYITDMFFARAGVEAMYNIDNGNTEWGPTVGLGLNFGGS
GGKVEAAPAPVAEVCSDSDNDGVCDNVDKCPDTPANVTVDADGCPAVAEVVRVELDVKFD
FDKSVVKPNSYGDIKNLADFMKQYPQTTTTVEGHTDSVGPDAYNQKLSERRANAVKQVLT
NQYGVESSRVESVGYGETRPVADNATDAGRAVNRRVEAQVEAQAK