Protein Info for CCNA_03871 in Caulobacter crescentus NA1000 Δfur

Annotation: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 PF00890: FAD_binding_2" amino acids 6 to 36 (31 residues), 23.6 bits, see alignment (E = 7.1e-09) PF12831: FAD_oxidored" amino acids 6 to 49 (44 residues), 28.1 bits, see alignment 3.5e-10 PF01134: GIDA" amino acids 6 to 396 (391 residues), 549.2 bits, see alignment E=1.4e-168 TIGR00136: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA" amino acids 6 to 613 (608 residues), 815.1 bits, see alignment E=1.8e-249 PF21680: GIDA_C_1st" amino acids 459 to 549 (91 residues), 68.7 bits, see alignment E=1.5e-22 PF13932: GIDA_C" amino acids 553 to 609 (57 residues), 82.8 bits, see alignment 2.9e-27

Best Hits

Swiss-Prot: 100% identical to MNMG_CAUVC: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (mnmG) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03495, glucose inhibited division protein A (inferred from 100% identity to ccs:CCNA_03871)

Predicted SEED Role

"tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GW33 at UniProt or InterPro

Protein Sequence (618 amino acids)

>CCNA_03871 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA (Caulobacter crescentus NA1000 Δfur)
MSKSWDVIVIGGGHAGCEAAAASARAGARTLLLTHKLETIGEMSCNPAIGGLGKGHLVRE
IDALDGVMGRMADKAGIQFRMLNRSKGPAVRGPRSQIDRRLYREAMQAELFSTGNLDIIA
AAAEDLIVEDGKVAGAVDAAGQAYRAPRVILTTGTFLKGVIHRGEDRIPAGRVGDQPAIG
LSDRLYGLGFQMGRLKTGTPARLDGKTIAWDRLESQAADDTPVPFSYLNHRIDVPQIACG
VTYTTEETHRIIAERIGESLVYSGRATGVGPRYCPSIEDKVVRFADKTSHQIFLEPEGLD
DDTVYPNGISTSVSEETQLLFLRTIPGLEQVEVIRYGYAIEYDYVDPRELYPTLETKRLP
GLYLAGQINGTTGYEEAGAQGLVAGLNAALAVQGREPAIFARDEAYIGVMIDDLVTRGVT
EPYRMFTSRAEFRLTLRADNADQRLSDRGISLGVVGPVRAAAWTEKKARLDAARAFARSV
TLTPNEAVKAGFKVNSDGVRRDVFAMLAYPDVTLDDLGRIWPEVFTWNTDVREQIEIEAA
YAGYLDRQRADAESLRKDEDLRLPADLDYAEIGSLSNEVRGKLARVRPLTLGQAARIEGV
TPGALTALLAHVRRGRAA