Protein Info for CCNA_03802 in Caulobacter crescentus NA1000 Δfur

Annotation: serine protease, peptidase family S9A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 718 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 47 to 447 (401 residues), 133.4 bits, see alignment E=1.5e-42 PF00326: Peptidase_S9" amino acids 515 to 716 (202 residues), 156.8 bits, see alignment E=8.6e-50

Best Hits

Swiss-Prot: 54% identical to Y4NA_SINFN: Uncharacterized peptidase y4nA (NGR_a02410) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K01322, prolyl oligopeptidase [EC: 3.4.21.26] (inferred from 100% identity to ccs:CCNA_03802)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.26

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CD87 at UniProt or InterPro

Protein Sequence (718 amino acids)

>CCNA_03802 serine protease, peptidase family S9A (Caulobacter crescentus NA1000 Δfur)
MRKSLLALLASTSLMTLTPAIAADTAKPAGKPAAEARTPLSELGKDDPYLWMEEIEGTRA
MDWAKAQNARSLPVLQGDARYADLESKALAILNAKDRVPGVSFAGDGSLRNFWQDKDHVR
GIWRKTTLDSYRTAEPAWETILDIDALTKAENANWVFKGASCLPPEDTRCLITLSNGGKD
AVTVREFDTTTKTFVPGGFELPEGKQNYTWLDKDTLLVGREWKPGELTKSGYAYVLKALK
RGQPLDQAKEVFRGVETDVSVSPFVLRDADGKAVAVMATRGVTFFESETYLIEGDKPVKL
DLPLKSSIQGYVDGQMVVLMEQDWPAKGFKVGDLISFDLAKLKAAPDKAVATLVLRPTAL
QSVEQVQTTRTKLVVGMLDNVKGAAKVFTHGPKGWTAQTLDLPANSAIGLGSSDDKGERL
FVTVTGYLTPTTFWLADAGSLKLEQIKASPARFDASTHVVEQFEATSTDGTKVPYFVVRP
KDVKYDGSAPTLLYAYGGFQVPLTPGYSGTMGKLWLERGGVYVVANIRGGGEFGPAWHSA
GLKENRQKVYDDFFAVSQDLITRKITSPRRLGIMGGSNGGLLMGVALTQRPELYNAIVVQ
VPLFDMIRYSQIGAGASWVGEYGDPAIPSELAVIAKYDPYSNLKAGQKYPEVFIETSTKD
DRVHPAHARKAAARLMELGYPVLYYENVDGGHAASANLAETARRQALEYVYLTRKLMD