Protein Info for CCNA_03219 in Caulobacter crescentus NA1000 Δfur
Annotation: cation/multidrug efflux pump acrB5
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03219)Predicted SEED Role
"RND multidrug efflux transporter; Acriflavin resistance protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H3CCP7 at UniProt or InterPro
Protein Sequence (1022 amino acids)
>CCNA_03219 cation/multidrug efflux pump acrB5 (Caulobacter crescentus NA1000 Δfur) MKFDLSTFAVRRWQFTLVAFGLLVMLGFNAFTSIPRSEDPHFPIPIVIVRAVLPGAEPSE MEQLVVDPIEDAVDGLDNIEKVESVSLDGAAVVSVHFTWDVDPERKYDQVVREVNAIRGN LPTGLARLDIQRARTTEVSVVQVALTSDTLPMRRLEKVADRLRERLDRVPGVREAQYWGA PPSDVQVTLDLARLSALKLPATAVTDALRAAGAEAPIGAVQAGERRFNVKSGGAFRDLKT IGDTPVRSIGGKVVRVSDVATIGWAQQEPTHVTRFNGKRAVFITVKQKDGQDVAKITQEV RKVLDEYERALPAGVKLERAFFQAENVKHRLKNLFRDFGIALVLVLITLLPLGPRAGVVV MVSIPLSLLIGLSMLQAFGFTLNQLSIAGFVLSLGLLVDDSIVITENIARRIREGEERTE AAVNGARQIGLAVVGCTATLMLAFLPLMALPAGSGAYIKSLPVTVLCTVGASLLVSLTII PFLASRILDKHSDPEGNALLRAVNGGIQRFYRPVLHASLARPWLALALMLALCATTVPLV KVIGSSLFPPAETPQFLIRIETPDGASLARTDQALRFVDARLAKEPEILWRASNLGRGNP QIFYNKTQRESSNSFAEVYASFEAWKPGKSDKVLDALRADFAKYPGARITVVAFENGPPI DAPIAIRITGQNLEVLKALAARTEAALKDTPGARDVSNPMRLDRTDLDLGVDEAKAAALG VPAGAARRVTRLALSGEEAARFRDPDGDDYAVRVRLPTAQVDGAARNPLSALNGVYVPTA EGEAAPLGAIATPTLRSSPARIDRFDRERTVTVTSYVATGYLTAKVTQDVVQRLEKEVPM PPGYRLSLGGQAEAQSESFAGLGAAVLVAIFGILAVLVLEFQKFKTALVVAGIIPFGIFG AVLALALTGNSLSFTATIGLIALIGIEIKNSILLVDFTEQLRREGMNLHDAIEKAGEVRF LPVLLTSVTAIGGLLPLALERSGLYSPLAIAIIGGLITSTLLSRVATPVMYWLTARGKAE AV