Protein Info for CCNA_03095 in Caulobacter crescentus NA1000 Δfur

Annotation: small-conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 62 to 83 (22 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details PF21088: MS_channel_1st" amino acids 71 to 108 (38 residues), 27.9 bits, see alignment 2.8e-10 PF00924: MS_channel_2nd" amino acids 110 to 176 (67 residues), 62.4 bits, see alignment E=5.4e-21 PF21082: MS_channel_3rd" amino acids 186 to 272 (87 residues), 31.5 bits, see alignment E=3e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03095)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CBE1 at UniProt or InterPro

Protein Sequence (341 amino acids)

>CCNA_03095 small-conductance mechanosensitive channel (Caulobacter crescentus NA1000 Δfur)
MDENPLRTLDSFELLKLGKASVTVGSLTTGLLIVLAALFAARITSAGLRRLRQKAGGNAA
SLYVVEKVAGYSLVVVGVMAGLSTMGLDLTSLTVFAGALGVGVGLGLQGVIKDFASGVSL
VFERLVAVGDFVELPNGGRGVVHEIGPRATRIRTNDSTDIIVPNSVLVNDQVINWTLRGT
NRRLRVPFVTAFGTDKEKVREAVLKAAKAAPFTSPDDATRRAQVWLVGYGESSLKFELVV
WPTVEAVRRPAAIFAAYTWLIDDALREAGIEIPYPQRDIRLRGLFGEEGEEAMASLRLEP
AARRRKASKAARIGSSNDAAADLEREDPEEAPKVPPPPERR