Protein Info for CCNA_03035 in Caulobacter crescentus NA1000 Δfur

Annotation: TadC-related pilus assembly protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 transmembrane" amino acids 48 to 69 (22 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 179 to 202 (24 residues), see Phobius details amino acids 333 to 355 (23 residues), see Phobius details PF00482: T2SSF" amino acids 222 to 350 (129 residues), 66.6 bits, see alignment E=1e-22

Best Hits

KEGG orthology group: K12511, tight adherence protein C (inferred from 100% identity to ccr:CC_2940)

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CC31 at UniProt or InterPro

Protein Sequence (362 amino acids)

>CCNA_03035 TadC-related pilus assembly protein (Caulobacter crescentus NA1000 Δfur)
MFWLPRRVRFQGVCGFDLDPGIRREGRRWRMGEGRMSLVETLTSPSNVLTAFIAVVVFAT
IITLASPVMRDNNLEGRLKSVANRREELRRRSRQSISTRAPGTAGGTLRHQDEGLYKNVV
ERLQLSRLLEDPKVVEKLAQAGFRGPKPVSTFYFFRFAMPFAFAAGAAFYLYVVNDFGLL
PMQKLCACVAFLALGYYAPNVYISNVAQKRRESIVAAFPDALDLLLICVESGMSIEAAIQ
KVGAEVGSSSMELAEELSLLTAELSYLPDRRLAYENLARRTNHPGIKSVATAMIQAERYG
TPLGTALRVMAKENRELRLSAAEKKAAALPAQLTVPMILFFLPVLFIMILGPAIMKVQDA
FK